Displaying 301 - 320 of 853
| Active Ingredient | DILTIAZEM |
| Therapeutic Class | CCBs, MISCELLANEOUS |
| Indications | Class IV antiarrhythmic. |
| Caution | Headache, ankle oedema, hypotension, dizziness, bradycardia, AV block. Avoid grapefruit juice. C.f. Prescribing in liver and renal disease p. 13; 28. |
| Dose Range |
Angina: 60-120mg three times daily to a maximum of 360mg daily . Slow release preparation:120-480mg daily . |
| Drug Interactions | |
| Pregnancy | Diltiazem should be used during pregnancy only when the possible benefits outwei More ... |
| Breast Feeding | Diltiazem is distributed in breastmilk and is not recommended for lactating wome More ... |
| Active Ingredient | VERAPAMIL |
| Therapeutic Class | CCBs, MISCELLANEOUS |
| Indications | Class IV antiarrhythmic. |
| Caution | Do not combine with beta blockers. Nausea, vomiting, hypotension. Avoid grapefruit juice. Concurrent use with caffeine may result in enhanced CNS stimulation. C.f. prescribing in liver disease p. 18. |
| Dose Range |
Arrhythmias: 120-480mg 3-4 divided doses. Inj. 5-10mg slow i.v. over 2-3 minutes (preferably with ECG monitoring); Angina: 120mg 3 times daily or sustained release as 120-240mg once daily . |
| Drug Interactions | |
| Pregnancy | Verapamil crosses the placenta and can potentially cause fetal harm. Use during More ... |
| Breast Feeding | Verapamil is distributed in breastmilk. Use is not recommended for lactating wom More ... |
| Active Ingredient | ACE INHIBITORS |
| Therapeutic Class | ACE INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CAPTOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Essential hypertension, congestive heart failure, diabetic nephropathy in patients with type 1 diabetes mellitus with retinopathy . |
| Caution | See notes on page 215. Dry cough, loss of taste, dry mouth, hypotension, drug fever, and rash. C.f. prescribing in renal disease p. 24. |
| Dose Range |
Hypertension: Initially 12.5mg twice daily to a maintenance dose of 25-50mg twice daily . Max. of 50mg 3 times daily is rarely needed. Diabetic nephropathy: Usual dose 25mg 3 times daily . CHF: 6.25- 12.5mg 2-3 times daily.See BDS supply protocols pg. |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Captopril is distributed into breastmilk and is not recommended in lactating wom More ... |
| Active Ingredient | ENALAPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Congestive heart failure, essential hypertension. |
| Caution | Headaches, dizziness and fatigue. See notes on page 215. c.f. prescribing in renal disease p. 28. |
| Dose Range | Hypertension: Initial dose 5mg preferably at bedtime when used alone or 2.5mg with a diuretic. Maintenance dose: 10-20mg daily.Maximum 40mg daily. Congestive Heart Failure: Initial dose 2.5mg daily, usual maintenance dose 20mg as a single or 2 divided d |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Enalapril is distributed in breastmilk and is not recommended in lactating women More ... |
| Active Ingredient | INDAPAMIDE | PERINDOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications |
Mild to moderate hypertension. Edema from congestive heart failure. Not to be used for diuresis. |
| Caution | It may take 2-3 months before optimal blood pressure levels are reached on one tablet daily . An increase in the dosage does not cause any greater reduction in blood pressure. Do not use More ... |
| Dose Range | Adult: One tablet daily before breakfast. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | LISINOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Hypertension. Congestive heart failure. Myocardial Infarction. |
| Caution | See notes on page 215. headache and dizziness.c.f. prescribing in renal disease p. 31. |
| Dose Range |
Hypertension: Initial dose 10mg daily ,if used in addition to diuretic or in cardiac decomp ensation or in volume depletion, initially 2.5-5 mg once daily; Maintenance dose: 20mg once daily. CHF: 2.5mg daily to 5 - 40mg daily. After myocardial infarc |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Lisinopril is excreted in breastmilk and is not recommended in lactating women. |
| Active Ingredient | PERINDOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | RAMIPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Mild to moderate hypertension, congestive heart failure. |
| Caution | Nausea, cough, asthenia, abdominal cramps, headache, dizziness. C.f. prescribing in renal disease p. 36. |
| Dose Range | Hypertension: 2.5-10mg once daily. CHF: Initial dose 1.25mg once daily increased to 10 mg daily in 1 or 2 divided doses. After myocardial infarction: Initial dose 2.5 mg twice daily ,increased after two days to 5 mg twice daily. Renal impairment: Initial |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Use ramipril with caution in lactating women. |
| Active Ingredient | LOSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | Hypertension and heart failure, particularly in patients who develop cough with ACE inhibitors. |
| Caution |
Headache, upper respiratory infection, dizziness and cough. Cough, dizziness, edema and nausea, vomiting were significantly more frequent in patients aged 76 years and over. |
| Dose Range | Adult: 25-100mg orally once or twice daily is effective as either monotherapy or in combination with other antihypertensives (diuretics in p articular) in mild to moderate hypertension. See BDS supply protocols pg. 7. |
| Drug Interactions | |
| Pregnancy | Drugs that act on the angiotensin system can cause injury and death to the devel More ... |
| Breast Feeding | Avoid breastfeeding during use of losartan. |
| Active Ingredient | SACUBITRIL | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | Sacubitril and valsartan in fixed combination is used to reduce the risk of cardiovascular death and hospitalization for patients with chronic heart failure (New York Heart Association [NYHA] class 11 More ... |
| Caution | A history of angioedema with an ACE inhibitor or angiotensin 11receptor antagonist. Concomitant use with ACE inhibitors. Sacubitril/valsartan should not be administered within 36 hours of switching f More ... |
| Dose Range | Adult: The recommended initial dose of sacubitril /valsartan in patients with CHF who are stabilised on an ACE or ARB is sacubitril 49mg /valsartan 51 mg twice daily. 36 hours should have relapsed before starting sacubitril/valsartan, if patient was on a |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | TELMISARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications |
Hypertension, left ventricular dysfunction after my ocardial infarction, heart failure when ACE inhibitors are not tolerated. |
| Caution | Headache, dizziness, viral infection, upper respiratory tract infection, cough, diarrhea, drowsiness, rhinitis, sinusitis, backache, stomach ache, nausea, pharyngitis and joint pain. The drug is contr More ... |
| Dose Range | Hypertension: Initial dose 80mg once daily, with or without food. The dose may be increased to 160mg daily if initial response is insufficient. Maximum dose 320mg once daily. CHF: Initially 40mg twice daily increased as tolerated to 160mg twice. M |
| Drug Interactions | |
| Pregnancy | Drugs that act on the angiotensin system can cause injury and death to the devel More ... |
| Breast Feeding | Avoid breastfeeding while using losartan. |
| Active Ingredient | EPLERENONE |
| Therapeutic Class | ALDOSTERONE RECEPTOR ANTAGONIST |
| Indications | Hypertension, Chronic heart failure (NYHA class II-IV) with reduced ejection fraction |
| Caution | Hyperkalemia, Hypercholesterolaemia, hypertriglyceridaemia |
| Dose Range | Hypertension: Initially 50mg daily increased to a maximum of 50mg twice a day. HF: Initially 25mg daily, increased in 25mg increments, if tolerated, to a maximum of 50mg daily in a 4 week period. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SPIRONOLACTONE |
| Therapeutic Class | ALDOSTERONE RECEPTOR ANTAGONIST |
| Indications | Oedema in Congestive Heart Failure (CHF).It is frequently given with the thiazides, furosemide, or similar diuretics, where it adds to their natriuretic but diminishes their kaliuretic effects, he More ... |
| Caution |
May cause hyperkalemia in renal failure; gynaecomastia, nausea, vomiting, drowiness. C.f. prescribing in renal disease p. 36. |
| Dose Range |
Adults and Children over 12yrs: Odema: 100-200mg daily in single or divided doses to a maximum of 400mg daily. Moderate to severe heart failure (Adjunct): initially 25mg increased to a maximum of 50mg once daily . Pediatric 1mth-12yrs: 1-3mg/kg in 1 or 2 |
| Drug Interactions | |
| Pregnancy | Safe use of spironolactone during pregnancy has not been established. The drug s More ... |
| Breast Feeding | Spironolactone enters breastmilk and is not recommended in lactating women. |
| Active Ingredient | IDARUCIZUMAB |
| Therapeutic Class | ANTIDOTAL AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GENERAL ANAESTHETICS |
| Therapeutic Class | GENERAL ANESTHETICS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | THIOPENTONE SODIUM |
| Therapeutic Class | BARBITURATES (ANAESTHETICS) |
| Indications | Induction of general anaesthesia; anaesthesia of short duration. |
| Caution | Induction: 50-100mg intermittently every 30-40 seconds or as a single dose 3-5 mg/kg injection. |
| Dose Range | c.f. prescribing in liver disease p. 18. |
| Drug Interactions | |
| Pregnancy | May depress neonatal respiration when used during delivery. |
| Breast Feeding | Breast-feeding can be resumed as soon as mother has recovered sufficiently from More ... |
| Active Ingredient | DESFLURANE |
| Therapeutic Class | INHALATION ANAESTHETICS |
| Indications | Maintenance of general anaesthesia. |
| Caution | Respiratory depression, hypotension, and arrhythmias may occur. |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ISOFLURANE |
| Therapeutic Class | INHALATION ANAESTHETICS |
| Indications | General Anaesthetic. |
| Caution | Isoflurane potentiates all commonly used muscle relaxants; therefore less than usual amounts of such agents are recommended. |
| Dose Range | Induction: 0.5-3% in oxygen or nitrous oxide-oxygen. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |