Active Ingredient | ANTIHISTAMINICS |
Therapeutic Class | ANTIHISTAMINICS |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | CHLORPHENIRAMINE |
Therapeutic Class | FIRST GENERATION ANTIHISTAMINE |
Indications | Hay fever, allergic rhinitis, urticaria (prevention and treatment) and pruritis associated with skin disorders; emergency treatment of anaphylactic reactions. |
Caution | Dryness of mouth. Injections may be irritating and may cause transient hypotension. May cause drowsiness, if affected do not drive or operate machinery; avoid alcohol. |
Dose Range |
4-24mg in divided doses. Slow I.V . injection, SC or I.M: 10- 20mg, repeated if required. Maximum: 40mg in 24 hours. Pediatric: Not recommended under 1 year, 1-2 y ears 1mg twice daily , 2-6 years 1mg every 4-6 hours, maximum of 6mg daily , 6-12 years 2mg |
Drug Interactions | |
Pregnancy | Use in the latter part of the third trimester may cause adverse effects in neona More ... |
Breast Feeding | Most antihistamines are present in breast milk in varying amounts; although not More ... |
Active Ingredient | CHLORPHENIRAMINE | PSEUDOEPHEDRINE |
Therapeutic Class | FIRST GENERATION ANTIHISTAMINES |
Indications | Hay fever, allergic rhinitis, urticaria (prevention and treatment) and pruritis associated with skin disorders; emergency treatment of anaphylactic reactions. |
Caution | Dryness of mouth. Injections may be irritating and may cause transient hypotension. May cause drowsiness, if affected do not drive or operate machinery; avoid alcohol. |
Dose Range | Adult: 4-24mg in divided doses. Slow I.V. injection ,S.C or I.M : 10-20mg, repeated if required. Maximum: 40mg in 24 hours. Pediatric: Not recommended under 1 year, 1-2 years 1mg twice daily, 2-6 years 1mg every 4-6 hours, maximum of 6mg daily, 6-12 year |
Drug Interactions | Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. |
Pregnancy | |
Breast Feeding |
Active Ingredient | DIPHENHYDRAMINE |
Therapeutic Class | FIRST GENERATION ANTIHISTAMINES |
Indications | Motion sickness, extrapyramidal symptoms; antitussive,severe allergic reactions. |
Caution | See Chlorpheniramine Maleate |
Dose Range |
Adult: 25-50mg 3-4 times daily. Maximum dose 300mg daily . Pediatric: 2-6 years: 6.25 mg every 4-6 hours; 6-12 years: 12.5 - 25 mg every 4-6 hours. |
Drug Interactions | |
Pregnancy | Use of diphenhydramine during the first trimester of pregnancy has been associat More ... |
Breast Feeding | Diphenhydramine has been detected in milk. A decision should be made whether to More ... |
Active Ingredient | CETIRIZINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | Allergic rhinitis, chronic urticaria. |
Caution | May cause drowsiness. Use with caution in patients with hepatic or renal impairment. |
Dose Range |
Adult and Children 6 years and over: 10mg once daily or in 2 divided doses. Pediatric: 2-5 years: 5 mg daily as a single dose or in 2 divided doses. |
Drug Interactions | Cetirizine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase so More ... |
Pregnancy | |
Breast Feeding | Most antihistamines are present in breast milk in varying amounts; although not More ... |
Active Ingredient | CETIRIZINE | PSEUDOEPHEDRINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | Cetirizine and pseudoephedrine is a combination medicine used to treat cold or allergy symptoms such as nasal and sinus congestion, sneezing, itching, watery eyes, or runny nose. |
Caution | You should not use cetirizine and pseudoephedrine if you have narrow-angle glaucoma, severe high blood pressure (hypertension), severe coronary artery disease, if you are unable to urinate, |
Dose Range |
Usual Adult Dose for Allergic Rhinitis: Cetirizine 5 mg/ pseudoephedrine 120 mg per tablet: 1 tablet orally every 12 hours Maximum dose: 2 tablets per 24 hours Usual Pediatric Dose for Allergic Rhinitis: Cetirizine 5 mg/ pseudoephedrine 120 mg per table |
Drug Interactions | |
Pregnancy | It is not known whether cetirizine and pseudoephedrine will harm an unborn baby. |
Breast Feeding | Cetirizine and pseudoephedrine may pass into breast milk and may harm a nursing More ... |
Active Ingredient | CLEMASTINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | Allergic dermatosis, rhinitis. |
Caution | See Chlorpheniramine Maleate. |
Dose Range |
Adult: 1-2 tablets once or twice daily, maximum dose 6mg daily . Pediatric:1-3yrs- 0.25-0.5mg twice daily, 3-6 yrs- 0.5mg twice daily , 6-12yrs 0.5-1mg twice daily. See BDS supply protocols pg. 8. |
Drug Interactions | |
Pregnancy | Use in the latter part of the third trimester may cause adverse effects in neona More ... |
Breast Feeding | Most antihistamines are present in breast milk in varying amounts; although not More ... |
Active Ingredient | DESLORATADINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | FEXOFENADINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | FEXOFENADINE | PSEUDOEPHEDRINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | LEVOCETIRIZINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | LORATADINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | For the treatment of chronic idiopathic urticaria. |
Caution | The most common side effects are headache and nausea. Co- administration of loratadine with drugs that inhibit the cytochrome P450 system will result in an increase in plasma concentrations of lorata More ... |
Dose Range |
Adults and children 6 years and older: 10mg once daily. Pediatric: 2-5 years: 5mg once daily. Dosage adjustment is necessary in patients with liver and renal insufficiency. |
Drug Interactions | |
Pregnancy | |
Breast Feeding | Most antihistamines are present in breast milk in varying amounts; although not More ... |
Active Ingredient | MEQUITAZINE |
Therapeutic Class | SECOND GENERATION ANTIHISTAMINES |
Indications | Symptomatic relief of allergic conditions such as, urticaria, rhinitis and conjunctivitis. |
Caution | May cause drowsiness. Warn patients against ingesting alcohol, driving and operating heavy machinery. Dry mouth. |
Dose Range | Adult: 5mg twice daily . |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | ANTIINFECTIVES |
Therapeutic Class | ANTI-INFECTIVE AGENTS |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | ALBENDAZOLE |
Therapeutic Class | ANTHELMINTICS |
Indications | Threadworm, Whipworm, Roundworm, Strongyloides, Hookwormand Pinworm, neurocysticercosis |
Caution | Gastrointestinal discomfort, headache. Do not use during pregnancy. Use an effective form of birth control while taking this medicine and for at least one month after your last dose. Patients being tr More ... |
Dose Range | Adults and Children 2 years and over: 400mg as a single dose. Strongyloides: 400mg as a single dose for 3 consecutive days. Cutaneous Larva Migrans: 400mg daily for 3 days. Neurocysticercosis: 2 tablets twice daily for patients over 60kg. Under 60 |
Drug Interactions | |
Pregnancy | Avoid use in pregnancy. |
Breast Feeding |
Active Ingredient | LEVAMISOLE |
Therapeutic Class | ANTHELMINTICS |
Indications | |
Caution | |
Dose Range | |
Drug Interactions | |
Pregnancy | |
Breast Feeding |
Active Ingredient | MEBENDAZOLE |
Therapeutic Class | ANTHELMINTICS |
Indications | Threadworm, roundworm, hookworm and whipworm |
Caution | Cramps and diarrhoea, rash, headache. Avoid in pregnancy and in infants. Pyrexia, constipation, headache, dizziness, itching, swelling of face or mouth. Tablets may be chewed, swallowed or crus More ... |
Dose Range | Adult and children 2 years and over: Threadworm 100mg as a single dose. Repeat regimen in 3 weeks if necessary. Whip worm, roundworm, hookworm 100mg twice daily for 3 consecutive days. |
Drug Interactions | |
Pregnancy | Avoid use in pregnancy. |
Breast Feeding | Amount present in milk too small to be harmful but manufacturer advises avoid. |
Active Ingredient | GENTAMICIN |
Therapeutic Class | AMINOGLYCOSIDES |
Indications | Septicaemia and neonatal sepsis, biliary infections, intraabdominal and UTI, acute pyelonephritis. Severe gram-negative infections, primarily pseudomonas infections. |
Caution | Increase dose interval in renal impairment in children and the elderly. Use nomogram (see renal disease guidelines p.19-38) and check peak (1 hour) and trough (predose) levels. Nehrotoxicity or ototo More ... |
Dose Range |
i.m. 3-5mg/kg/day in divided doses every 8 hours for 7-10 days. 12 hours (clearance 30-70 ml/min), 24 hours (clearance 10-30ml/min, 48 hours (clearance 5-10ml/min) |
Drug Interactions | |
Pregnancy | Risk of auditory or vestibular nerve damage in the infant when aminoglycosides a More ... |
Breast Feeding |
Active Ingredient | TOBRAMYCIN |
Therapeutic Class | AMINOGLYCOSIDES |
Indications | Septicaemia and neonatal sepsis, biliary infections, endocarditis, acute pyelonephritis. Tobramycin is slightly more effective for Pseudomonas aeruginosa than gentamicin, but shows less activity agai More ... |
Caution | Nephrotoxicity and ototoxicity occur with high concentrations. It is less toxic than gentamicin. The dose should be reduced in renal failure and in the elderly. C.f. prescribing in renal disease p. 3 More ... |
Dose Range |
Adult: 3-5mg/kg/day divided every 8 to 12 hours based on renal function and serum tobramy cin levels: or once-daily administration is 4-7mg/kg/day; higher doses may be needed depending on the diagnosis. Pediatric 1 mth- 12 yrs: 2-2.5mg/kg every 8 hours. |
Drug Interactions | |
Pregnancy | Risk of auditory or vestibular nerve damage in the infant when aminoglycosides a More ... |
Breast Feeding |
Active Ingredient | CEFADROXIL |
Therapeutic Class | FIRST GEN CEPHALOSPORINS |
Indications | Oral cefadroxil is used for the treatment of pharyngitis and tonsillitis caused by Streptococcus pyogenes. Inactive against Pseudomonas and Bacteroides. |
Caution | Nausea and vomiting, hypersensitivity in about 10% of penicillin sensitive patients otherwise little toxicity. Note high cost of cephalosporins. Best used for specifically identified susceptible o More ... |
Dose Range | Adult: 1-2g daily as a single dose or in two divided doses. Pediatric: Under 1 year: 25mg/kg in divided doses; 1-6 years: 250mg twice daily; over 6 years: 500mg twice a day. See BDS supply protocols pg.3. |
Drug Interactions | |
Pregnancy | |
Breast Feeding | Present in milk in low concentration, but appropriate to use. |