Displaying 61 - 80 of 853
Active Ingredient CLINDAMYCIN PHOSPHATE
Therapeutic Class LINCOMYCINS
Indications Staphylococcal bone or joint sepsis, peritonitis (alternative to gentamicin and metronidazole). Effective against many anaerobes. Bacteroides fragilis. Gram-positive cocci including penicillin-resista More ...
Caution Diarrhoea, pseudomembranous colitis. This is the commonest antibiotic causing it (responds to oral metronidazole or vancomycin). Report any excess diarrhoea, do not take anti-diarrhoeal drugs.
Dose Range Adult: 150-450mg every 6 hours. Pediatricunder12 years: 3-6 mg/kg/day every 6 hours.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ANTIFUNGALS
Therapeutic Class ANTIFUNGALS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient TERBINAFINE
Therapeutic Class ALLYAMINES
Indications Onychomycosis.Indicated for onychomycosis of the toenail or fingernail owing to dermatophytes (tinea unguium
Caution Headache, rash , nausea, diarrhea, dyspepsia, taste disturbance, elevated liver function test results, rarely, cases of liver failure, some leading to death or liver transplant.

Skin and subcutaneo More ...
Dose Range 250mg once daily for 6-12 weeks.
Drug Interactions
Pregnancy Manufacturer advises use only if potential benefit outweighs risk.
Breast Feeding Accumulation in breastmilk prohibits use.
Active Ingredient CLOTRIMAZOLE
Therapeutic Class AZOLES
Indications Vaginal and vulval candidiasis.
Caution Local irritation and contact dermatitis may occur.
Dose Range Insert one applicatorful nightly of 1% cream for 7-14 nights, 2% cream for 3 nights, 10% cream stat dose or 200mg ovules into the vagina for 3 consecutive nights or 100mg ovule for 6 nights. Continue use during menstrual period.
Drug Interactions
Pregnancy Pregnant women need a longer duration of treatment, usually about 7 days, to cle More ...
Breast Feeding
Active Ingredient ECONAZOLE
Therapeutic Class AZOLES
Indications Yeast infections, candidiasis.
Caution Burning, stinging and erythema.
Dose Range 150mg once daily at bedtime for 3 consecutive nights. Continue use during menstrual period.
Drug Interactions
Pregnancy Pregnant women need a longer duration of treatment, usually about 7 days, to cle More ...
Breast Feeding
Active Ingredient FLUCONAZOLE
Therapeutic Class AZOLES
Indications Treatment of orophary ngeal and esophageal candidiasis, systemic candidal infections, vaginal candidasis, urinary tract infections, pneumonia, and peritonitis. Also, acquired immunodeficiency syndrome More ...
Caution Nausea, vomiting, diarrhoea, elevations in liver functions tests and alopecia. Low dose does not appear to increase risk of congenital abnormalities in t he first trimester.
Dose Range Oropharyngeal and esophageal candidiasis: 200mg on day 1 then
100mg PO/IV daily for at least 2 weeks. Systemic candidiasis:
400mg PO/IV once daily for 4 weeks and for at least 2 weeks orally after resolution of symptoms. Vaginal candidiasis: 150mg ora
Drug Interactions Clindamycin, Calcium channel blockers, Phenothiazines and Tricyclic antidepressants - increased risk of cardiotoxicity. Simvastatin and Cerivastatin - increased risk of Rhabdomyolysis. Amlodipi More ...
Pregnancy Avoid use in pregnancy. Multiple congenital abnormalities has been reported with More ...
Breast Feeding
Active Ingredient ISOCONAZOLE
Therapeutic Class AZOLES
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ITRACONAZOLE
Therapeutic Class AZOLES
Indications Treatment of vulvovaginal candidiasis, dermatophytoses unresponsive to topical treatment, systemic infections.
Caution Abdominal pain; diarrhoea, dysnoea; headache; hepatitis; hypokalaemia; nausea; rash; taste disturbances; vomiting.
Itraconazole should be avoided in patients with ventricular dysfunction or a history More ...
Dose Range Adult: Vulvovaginal candidiasis: 200mg twice daily for 1 day , Recurrent Vulvovaginal candidiasis: 50-100mg daily for 6 months. Systemic candidiasis: 100-200mg once daily .
Drug Interactions
Pregnancy Manufacturer advises use only in lifethreatening situations (toxicity at high do More ...
Breast Feeding Small amounts present in milk—may accumulate; manufacturer advises avoid.
Active Ingredient ITRACONAZOLE | SECNIDAZOLE
Therapeutic Class AZOLES
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient KETOCONAZOLE
Therapeutic Class AZOLES
Indications Vaginal candidiasis; prophylaxis of mycoses in immunosuppessed patients; systemic mycoses. To be used only in those patients who are resistant to fluconazole or terbinafine.
Caution Local irritation. Use with caution in patients with impaired hepatic function or adrenal reserve; blood dyscrasias, headache, dizziness, nausea, skin rash. The oral form may be taken with food or milk More ...
Dose Range Vaginal candidiasis: One ovule into the vagina at bedtime for 3 consecutive nights.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient MICONAZOLE
Therapeutic Class AZOLES
Indications Vaginal candidiasis
Caution Vaginal burning, irritation, contact dermatitis.
Dose Range One applicator full at night for 7 nights or 1 ovule at night for 3 nights.
Drug Interactions
Pregnancy Pregnant women need a longer duration of
treatment, usually about 7 days, to cle More ...
Breast Feeding
Active Ingredient VORICONAZOLE
Therapeutic Class AZOLES
Indications Invasive aspergillosis in immunocompromised patients; candidaemia, in non-neutropenic patients, fluconazole-resistant serious invasive candidiasis, oesophageal candidiasis, and serious fungal infecti More ...
Caution Visual disturbances, fever, rashes, nausea, vomiting, diarrhoea, abdominal pain, headache, sepsis, respiratory disorders, and peripheral oedema.
Dose Range IV: adults and adolescents: 6 mg/kg every 12 hours for the first 24
hours followed by maintenance dose of 4 mg/kg twice daily ; a lower dose of 3 mg/kg twice daily may be suitable for candidaemia in non- neutropenic patients or for deep tissue C
Drug Interactions
Pregnancy Because voriconazole can cause fetal harm, it should not be used during pregnanc More ...
Breast Feeding It is not known whether voriconazole is distributed into milk.
Active Ingredient CASPOFUNGIN
Therapeutic Class ECHINOCANDINS
Indications Invasive aspergillosis in patients refractory to, or intolerant of, other therapy. Invasive candidiasis; empirical therapy for presumed fungal infections in febrile, neutropenic patients.
Caution Diarrhoea, nausea, vomiting, flushing, headache, fever, tachycardia, venous complications around the infusion site. Possible histamine- mediated symptoms have included rash, facial swelling, pruritu More ...
Dose Range Adult: 70mg as a loading dose on the first day, followed by 50mg daily given as a slow IV infusion over 1 hour. Children: 70 mg/m2 loading dose on the first day, followed by 50 mg/m2 once daily thereafter given by intravenous infusion over about 1 hou
Drug Interactions
Pregnancy Use is not advised unless necessary.
Breast Feeding
Active Ingredient AMPHOTERICIN B
Therapeutic Class POLYENES
Indications Reserve for life threatening systemic fungal infections.
Caution Anemia, thrombocytopenia, CHF, anaphylaxis, fever, gastro-intestinal upset, nephrotoxicity (reduce with i.v. infusion of mannitol), tinnitus. Monitor Kidney Function. C.f. prescribing in renal disease More ...
Dose Range Adult and Children: i.v. 0.25mg/kg/day as a single dose, with
increments every other day to a maximum of 1.5 mg/kg/day .
Drug Interactions
Pregnancy Not known to be harmful but manufacturers advise avoid unless potential benefit More ...
Breast Feeding
Active Ingredient NYSTATIN
Therapeutic Class POLYENES
Indications For yeast infections; treatment of oral and vaginal candidiasis, and prophylaxis of intestinal candidiasis.
Caution Nausea, vomiting, diarrhoea (tablets), vaginal irritation
Dose Range Adult: 4-6mls 4 times daily. Pediatric: 100,000 units 3-4 times daily
after feeds or food and continued for 48 hours after lesions have healed. Retain suspension around in mouth for as long as possible, then swallow.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ANIDULAFUNGIN
Therapeutic Class ANTIFUNGALS, MISCELLANEOUS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CICLOPIROX OLAMINE
Therapeutic Class ANTIFUNGALS, MISCELLANEOUS
Indications Treatment of fungal infections, especially candidiasis.
Caution Burning or pruritus.
Dose Range Insert one applicatorful into the vagina at night, for 6 consecutive nights.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient GRISEOFULVIN
Therapeutic Class ANTIFUNGALS, MISCELLANEOUS
Indications Severe tinea infections. Not effective against candida albicans.
Caution Headache, gastrointestinal upset, rash, dry mouth, photosensitivity. Affects warfarin metabolism. Avoid in pregnancy, liver failure.
Dose Range Adult: 500mg-1g daily as a single dose or in divided doses (1g is for difficult to treat fungal infections) after meals for 30 days or more. Pediatric: 5-10mg/kg daily in 2 divided doses or as a single dose after meals. The oral suspension is reserved f
Drug Interactions
Pregnancy Griseofulvin studies have shown the drug to be embryotoxic and/or teratogenic in More ...
Breast Feeding Avoid use unless potential benefit outweighs risk.
Active Ingredient METRONIDAZOLE | MICONAZOLE
Therapeutic Class ANTIFUNGALS, MISCELLANEOUS
Indications Bacterial Vaginosis, Trichomonal Vaginitis, Vaginal Candidiasis .
Caution Vaginal burning, irritation. Not to be used during pregnancy particularly the first 3 months. Avoid alcohol during and for at least 24-48 hours after treatment.
Dose Range One applicatorful or one ovule at bedtime for 7 nights.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ANTITUBERCULARS
Therapeutic Class ANTIMYCOBACTERIALS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding