Formulary Monographs [CLEMASTINE, 0408]

CLEMASTINE
SECOND GENERATION ANTIHISTAMINES
Allergic dermatosis, rhinitis.
See Chlorpheniramine Maleate.
Adult: 1-2 tablets once or twice daily, maximum dose 6mg daily .
Pediatric:1-3yrs- 0.25-0.5mg twice daily, 3-6 yrs- 0.5mg twice daily ,
6-12yrs 0.5-1mg twice daily. See BDS supply protocols pg. 8.
Use in the latter part of the third trimester may cause adverse effects in neonates such as irritability, paradoxical excitability, and tremor.
Most antihistamines are present in breast milk in varying amounts; although not known to be harmful, most manufacturers advise avoiding their use in mothers who are breast-feeding.