Displaying 401 - 420 of 853
Active Ingredient METHYLPHENIDATE
Therapeutic Class RESPIRATORY-CEREBRAL STIMULANTS
Indications Attention deficit disorders; narcolepsy .
Caution Restlessness, vertigo, physical dependence, slurred speech.
Dose Range Narcolepsy: 10-60mg daily in 2-3 divided doses 30-45 minutes
before meals. Hyperkinetic states: Pediatric 6 and over: 5mg twice daily (immediate-release) before breakfast and lunch increased if necessary to 60mg daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ALPRAZOLAM
Therapeutic Class BENZODIAZEPINES (SEDATIVES)
Indications Indicated for anxiety and panic disorders.
Caution Adverse effects include dizziness, sleepiness, syncope, confusion, impaired memory and co-ordination, decreased libido, increased appetite, depression, and constipation. Withdrawal seizures may occur More ...
Dose Range Anxiety: 0.25-0.5mg 3 times daily increased if necessary to a total daily dose of 3 or 4mg. Panic disorders: 0.5-10mg daily divided into 3-4 doses. Elderly: initially 0.25mg 2 or 3 times daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CLOBAZAM
Therapeutic Class BENZODIAZEPINES (SEDATIVES)
Indications Adjunct in the treatment of epilepsy including seizures associated with the Lennox-Gastaut syndrome. Short-term treatment of acute anxiety.
Caution As for diazepam.
Dose Range Adult: Epilepy: 20 to 30 mg daily, maximum dose 60 mg daily . Acute anxiety: 10 to 30 mg daily may be taken in divided doses or as a single dose at night. Pediatric 6-17 years: initially 5 mg daily with a maintenance dose range of 0.3 to 1 mg/kg daily up
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient DIAZEPAM
Therapeutic Class BENZODIAZEPINES (SEDATIVES)
Indications Short term use as tranquilliser, sedative, and in status epilepticus, acute alcohol withdrawal. Also see chlordiazepoxide.
Caution See chlordiazepoxide above. Excessive drowsiness and confusion in
the elderly. Flumazenil as Anexate is available at the Q.E.H. for the treatment of benzodiazepine overdosage. C.f. prescribing in live More ...
Dose Range Anxiety: 2-30mg daily, usually best as a single night time dose.
Status epilepticus: 10-20mg i.v. at 5mg/minute. Repeat cautiously if necessary. Acute alcohol withdrawal: 10mg 3-4 times a day for
1 day, then 5mg 3-4 times a day when necessary .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient LORAZEPAM
Therapeutic Class BENZODIAZEPINES (SEDATIVES)
Indications Quick relief of anxiety symptoms but action not sustained. See p.
265.
Caution See Chlordiazepoxide Hydrochloride p. 319. It is habit forming and on sudden withdrawal may cause seizures. c.f. prescribing in liver disease p.15.
Dose Range Anxiety: 1-6mg daily in divided doses but may be gradually increased to 10mg daily in 2-3 divided doses. Elderly: Half adult dose. i.v 4mg given by slow intravenous injection.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient MIDAZOLAM
Therapeutic Class BENZODIAZEPINES (SEDATIVES)
Indications Sedation in minor surgical or investigative procedures and in intensive care, for premedication, and for induction of general anaesthesia.
Caution Dosage must be titrated carefully against the response of the patient; lower doses of midazolam are required when it is used with op ioid analgesics. Respiratory and cardiac function should be monitor More ...
Dose Range
Drug Interactions
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Active Ingredient NITRAZEPAM
Therapeutic Class BENZODIAZEPINES (SEDATIVES)
Indications Short term use for insomnia.
Caution Avoid prolonged ues. Use with cauion in heptic and renal impairment. Drowsiness, lightheadedness, disorientation, confusion. Effects may be more accentuated in elderly patients. c.f. prescribing in More ...
Dose Range Adult: 5-10mg at bedtime.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient BUSPIRONE
Therapeutic Class ANXIOLYTICS, SEDATIVES AND HYPNOTICS MISCELLANEOUS
Indications Short term treatment of anxiety disorders.
Caution Dizziness, nausea, headache, blurred vision, anger/hostility ,
lightheadedness, excitement. Avoid grapefruit juice. Safety and efficacy is not established in children under 18 yrs of age.
Dose Range Adult:5 mg 2 or 3 times daily increased in steps of 5 mg at 2 to 3- day intervals, if necessary , to 15 to 30 mg daily in divided doses.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CHLORAL HYDRATE
Therapeutic Class ANXIOLYTICS, SEDATIVES AND HYPNOTICS MISCELLANEOUS
Indications Short term treatment of insommia.
Caution G.I. upset. Dizziness, clumsiness, hangover effect. c.f prescribing in liver and renal disease p . 11; 25.
Dose Range Sedation: 250mg 3 times daily to maximum 2g daily . Insomnia:
500mg-1g 15-30 minutes before bedtime. Take with water or milk. Pediatric sedation: 1-12yrs: 30-50mg/kg maximum 1g 45-60mins preprocedure. 12-18yrs: 1-2g 45-60mins p re-p rocedure.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient HYDROXYZINE
Therapeutic Class ANXIOLYTICS, SEDATIVES AND HYPNOTICS MISCELLANEOUS
Indications Effective for alleviating 1g E-mediated pruritis and urticaria;
anxiety .
Caution Drowsiness, dry mouth, headache. C.f. prescribing in liver disease p. 14.
Dose Range Adults and children over 12yrs: Pruritis: initially 25mg at night,
increased if necessary to 25 mg 3-4 times daily ; Anxiety: 50-100mg daily in divided doses. Pediatric 1-6yrs: 1mg/kg or 5-15mg at night increasing to 50mg daily in divided doses. Pediatri
Drug Interactions
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Active Ingredient PROMETHAZINE
Therapeutic Class ANXIOLYTICS, SEDATIVES AND HYPNOTICS MISCELLANEOUS
Indications Pre-operative sedation, anti-emetic.
Caution CNS depression, dermatitis, drowsiness. c.f. prescribing in liver
disease p.17.
Dose Range Adult: 25-50mg daily as a single dose or in divided doses. Maximum 75mg. Pediatric 5-10 years:10mg at night and the following morning. I.M or IV: 25- 50mg as needed prior to surgery .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ZOLPIDEM
Therapeutic Class ANXIOLYTICS, SEDATIVES AND HYPNOTICS MISCELLANEOUS
Indications
Caution
Dose Range
Drug Interactions
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Active Ingredient ZOPICLONE
Therapeutic Class ANXIOLYTICS, SEDATIVES AND HYPNOTICS MISCELLANEOUS
Indications Insomnia (short -term use - up to 4 weeks).
Caution Bitter taste, residual sedation/p sy chomotor imp airment and rebound insomnia. The p otential of the drug to p roduce p hy sical dep endence have been reported; psychiatric reactions, including hall More ...
Dose Range Adult over 18: 7.5mg orally at bedtime. Elderly : initially 3.75mg at
bedtime increased if necessary . Start with small doses in severe renal impairment.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient LITHIUM CARBONATE
Therapeutic Class ANTIMANIC AGENTS
Indications Bipolar disorder: Acute manic p hases and for p rop hy laxis in manic
dep ressions.
Caution Ataxia and tremor, nausea, dry mouth, vomiting and diarrhoea. Blood level should be monitored and maintained in a safe therap eutic range of 0.5 to 1 meg/L. c.f. prescribing More ...
Dose Range Acute Mania:Controlled Release Preparations: 1800mg/day in 2-
3 divided doses. M aintenance 900-1200mg/day in 2-3 divided doses.
Immediate Release: 600mg three times daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ELETRIPTAN HYDROBROMIDE
Therapeutic Class SELECTIVE SEROTONIN AGONIST
Indications
Caution
Dose Range
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Active Ingredient RIZATRIPTAN
Therapeutic Class SELECTIVE SEROTONIN AGONIST
Indications Treatment of acute migraine
Caution Decreased alertness, diarrhoea; drowsiness; dry mouth; dy sp noea; headache; p alp itation; p araesthesia; p hary ngeal discomfort; sweating; tachy cardia; tremor.
Dose Range Adult: 10mg dose to be taken as soon as p ossible after onset, followed by 10mg after 2 hours if required, dose to be taken only if migraine recurs (p atient not resp onding to initial dose should not take second dose for same attack); maximum 20mg p e
Drug Interactions
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Active Ingredient SUMATRIPTAN
Therapeutic Class SELECTIVE SEROTONIN AGONIST
Indications
Caution
Dose Range
Drug Interactions
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Active Ingredient ZOLMITRIPTAN
Therapeutic Class SELECTIVE SEROTONIN AGONIST
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient FLUNARIZINE
Therapeutic Class ANTIMIGRAINE AGENTS MISCELLANEOUS
Indications Prophylaxis of migraine headache, peripheral vascular disease; vertigo.
Caution To be taken at bedtime to reduce CNS symptoms. Weight gain may occur in pediatrics. Sedation and drowsiness.
Dose Range Migraine Prophylaxis: 10mg at bedtime. Peripheral Vascular
Disease: 10-20mg daily . Vertigo: 20mg 3 times daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient BENZHEXOL
Therapeutic Class ANTICHOLINERGIC AGENTS (PARKINSONS)
Indications Parkinsonism, especially when tremor and salivation are marked. Drug induced parkinsonism but not tardive dyskinesia.
Caution Avoid if there is risk of urinary retention. Often abused by chronic
psychotics. Dry mouth, G.I. up set, blurred vision, nervousness and confusion.
Dose Range Adult: 1mg increased to 6-10mg daily in 3-4 divided doses (max.
20mg).
Drug Interactions
Pregnancy
Breast Feeding