| Active Ingredient | DEXTROSE | SODIUM CHLORIDE |
| Therapeutic Class | CALORIC AGENTS |
| Indications | Fluid and electrolyte replacement. |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SOYA BEAN OIL |
| Therapeutic Class | CALORIC AGENTS |
| Indications | Essential fatty acids deficiency and in Total Parenteral Nutrition. |
| Caution |
Prolonged or too rapid infusion of soya oil emulsion or its use in patients with imp aired fat metabolism has been associated with the ‘overload sy ndrome’. Soya p rotein-based infant feeds can More ... |
| Dose Range |
Emulsions of fractionated soy a oil containing 10, 20, or 30% are given by slow intravenous infusion as p art of total p arenteral nutrition regimes |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | DIURETICS |
| Therapeutic Class | DIURETICS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ACETAZOLAMIDE |
| Therapeutic Class | CARBONIC ANHYDRASE INHIBITORS |
| Indications | For adjunctive treatment of chronic simple (open angle) glaucoma, secondary glaucoma and pre op in acute angle closure glaucoma. |
| Caution | Confusion, Gastric irritation, hypokalaemia, parasthesia, loss of appetite. C.f. Prescribing in renal disease p . 22. May cause drowsiness. Not approved for use in children. |
| Dose Range | Adults: 250mg to 1g daily in divided doses orally or parenterally . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | FRUSEMIDE |
| Therapeutic Class | LOOP DIURETICS |
| Indications | Resistant oedema, renal failure, pulmonary oedema. |
| Caution | Fluid or electrolyte disturbances hyponatremia, hypotension, gout and glucose intolerance; deafness in renal failure; may precipitate prostatic urinary retention; toxicity with cephaloridine.c.f. pres More ... |
| Dose Range | Adults and Children over 12 years: 20-80mg up to a max. of 600mg in severe cases. May be more effective given twice daily . Slow i.v. 20-50mg. Pediatric 1 month-12 years: 0.5mg-2mg/kg, 2-3 times daily (500mg tablet available as a Category B at Q.E.H. Pharmacy for use by Consultant in renal dialysis unit only). |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | MANNITOL |
| Therapeutic Class | OSMOTIC DIURETICS |
| Indications | Forced diuresis, cerebral oedema. |
| Caution | Pulmonary odema, cardiac failure. May cause chills, fever. |
| Dose Range | 50-200g in infusion as 10% or 20% solution; over 24 hours, according to circumstances. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | BENDROFLUAZIDE |
| Therapeutic Class | THIAZIDE DIURETICS |
| Indications |
Mild cardiac failure and fluid retention, mild hypotensive and to potentiate other drugs in severe hypertension. For use only in patients who are hypocalcemic. |
| Caution | Fluid and electrolyte disturbances. [Hypokalemia, hyperuricaemia, hy p ergly caemia]. Diuretic-induced hypokalaemia may enhance the toxicity of digoxin unless adequate potassium supplementation is More ... |
| Dose Range |
Adult: Hypertension: 2.5mg daily . Paediatric: 50-100mcg/kg per day . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CHLORTHALIDONE |
| Therapeutic Class | THIAZIDE LIKE DIURETICS |
| Indications | Thiazides are used in the management of edema associated with heart failure, or a history of fluid retention, mild hypertension and to potentiate other hypertensive drugs in severe hypertension. |
| Caution | Alkalosis hypochloraemic; constipation; diarrhoea; dizziness; dry mouth; electrolyte imbalance; erectile dysfunction; fatigue; headache; hyperglycaemia; hyperuricaemia; nausea; postural hypotension; s More ... |
| Dose Range |
Oedema- Adult Initially 5–10 mg once daily or on alternate days, dose to be taken in the morning, then maintenance 5–10 mg 1–3 times a week. Hypertension - 2.5 mg daily, dose to be taken in the morning, higher doses are rarely necessary. |
| Drug Interactions | |
| Pregnancy | Thiazides and related diuretics should not be used to treat gestational hyperten More ... |
| Breast Feeding |
The amount present in milk is too small to be harmful. Large doses may suppress More ... |
| Active Ingredient | INDAPAMIDE |
| Therapeutic Class | THIAZIDE LIKE DIURETICS |
| Indications |
Mild to moderate hypertension. Edema from congestive heart failure. Not to be used for diuresis. |
| Caution | It may take 2-3 months before optimal blood pressure levels are reached on one tablet daily . An increase in the dosage does not cause any greater reduction in blood pressure. Do not use More ... |
| Dose Range | Adult: One tablet daily before breakfast. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | DIALYSIS SOLN |
| Therapeutic Class | IRRIGATING SOLUTIONS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GLYCINE |
| Therapeutic Class | IRRIGATING SOLUTIONS |
| Indications | Bladder irrigation during urological surgery . |
| Caution |
hemolytic anemia, thrombocytopenia and dysrhythmias with or without electrocardiagram changes. |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SODIUM CHLORIDE |
| Therapeutic Class | IRRIGATING SOLUTIONS |
| Indications | Sodium depletion, electrolyte imbalance. |
| Caution | Serum-electrolyte concentrations should be carefully monitored. |
| Dose Range | The concentration and dosage of sodium chloride solutions for intravenous use is determined by several factors including the age, weight and clinical condition of the patient and in particular the patients’ hydration state. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | WATER FOR INJ |
| Therapeutic Class | IRRIGATING SOLUTIONS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ALLOPURINOL |
| Therapeutic Class | URICOSURIC AGENTS |
| Indications | Prophylaxis of gout, hyperuricaemia. |
| Caution | May initially worsen symptoms in acute gout. Maculopapular rash. Adequate fluid intake needed. C.f. prescribing in renal disease p. 22. |
| Dose Range | Adult: Initially 100mg daily to a maintenance dose of 600mg daily (max.900mg daily ). For doses over 300mg take in divided doses. Pediatric under 15 yrs: 10-20mg/kg to a maximum of 400mg daily .Take with food. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | COLCHICINE |
| Therapeutic Class | URICOSURIC AGENTS |
| Indications | Acute gout, short term prophylaxis during initial therapy with allopurinol. |
| Caution | Diarrhea, stomach cramps, nausea. |
| Dose Range | Adult: Acute Gout: initially 1 mg, then 0.5mg no more frequent than every 4 hours until pain relief is obtained (max. dose 6 mg). Gout Prophylaxis: 0.5mg 2- 3 times daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PROBENECID |
| Therapeutic Class | URICOSURIC AGENTS |
| Indications |
Gout, gouty arthritis-hyperuricaemia. To increase penicillin and cephalosporin plasma levels by imp airing renal excretion. |
| Caution |
Ensure fluid intake of 2 litres per day. Avoid concurrent salicy lates. C.f. prescribing in renal disease p. 35. |
| Dose Range |
250-500mg twice daily, maximum 2g daily in 2-4 divided doses. Take with food. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | HYALURONIDASE |
| Therapeutic Class | ENZYMES |
| Indications |
As an adjunct to increase absorption and dispersion of injected drugs, subcutaneous infusions. Use controversial. |
| Caution | Sensitivity to hyaluronidase occasionally occurs. |
| Dose Range | 1500 units s.c. or i.m. mixed with injection fluid. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CODEINE |
| Therapeutic Class | ANTITUSSIVES |
| Indications | |
| Caution | |
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| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CODEINE PHOSPHATE | DIPHENHYDRAMINE | EPHEDRINE HCL |
| Therapeutic Class | ANTITUSSIVES |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CODEINE | DIPHENHYDRAMINE |
| Therapeutic Class | ANTITUSSIVES |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |