Displaying 381 - 400 of 853
Active Ingredient TIANEPTINE
Therapeutic Class ANTIDEPRESSANTS MISCELLANEOUS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CLOZAPINE
Therapeutic Class ATYPICAL ANTIPSYCHOTICS
Indications Schizophreniain patients unresponsive to, or intolerant of,
conventional antipsychotic drugs.
Caution Anorexia; constipation; hypersalivation; malaise; speech disorders; urinary incontinence.
Dose Range Adult:12.5 mg once or twice on the first day followed by 25 mg once or twice on the second day. Daily dosage may be increased gradually in step s of 25 to 50 mg. Maximum 900 mg per day . Adult 60 years and over: dose increments should be restricted to 2
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient OLANZAPINE
Therapeutic Class ATYPICAL ANTIPSYCHOTICS
Indications Schizophrenia, moderate to severe mania associated with bipolar disorder.
Caution Arthralgia, hypercholesterolaemia, hypertrigly ceridaemia, increased appetite, malaise, oedema.
Dose Range Adult: 5-20 mg daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient QUETIAPINE
Therapeutic Class ATYPICAL ANTIPSYCHOTICS
Indications Treatment of schizophrenia, bipolar disorder.
Caution Rate of dose titration may need to be slower and the daily dose lower in elderly patients. Asthenia; dysarthria; dyspnoea; elevated plasma-ca concentrations; elevated plasma-trigly ceride concentrati More ...
Dose Range Adult: Schizophrenia: 25 mg twice daily for day 1, then 50 mg twice daily for day 2, then 100 mg twice daily for day 3, then 150 mg twice daily for day 4, then, adjusted according to response, usual dose 300–450 mg daily in 2 divided doses. Maximum 750 mg
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient QUETIAPINE XR
Therapeutic Class ATYPICAL ANTIPSYCHOTICS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient RISPERIDONE
Therapeutic Class ATYPICAL ANTIPSYCHOTICS
Indications Manic bipolar I disorder, Schizophrenia.
Caution Increase body temperature, cerebrovascular accident in the elderly ,
drug-induced tardive dystonia, excessive thirst, hypergly cemia,hypothermia, seizure, syncope, tardive dyskinesia, transient isch More ...
Dose Range Manic bipolar I disorder: Monotherapy with lithium or valproate;
intially, 2-3mg orally once a day with dosage adjustments of
1mg/day increments. Schizophrenia: Initially 1mg twice daily ,
with 1mg twice daily increments on the second and third day
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ZIPRASIDONE
Therapeutic Class ATYPICAL ANTIPSYCHOTICS
Indications Schizophrenia, acute manic or mixed episodes associated with bipolar disorder.
Caution Orthostatic hypotension at the start of therapy. Somnolence,
urticaria, gastrointestinal disturbances, dizziness, flu-like symptoms, headache, agitation, confusion, dyspnoea.
Dose Range Adult: Schizophrenia: 20-80mg twice a day with food. Bipolar
Disorder: 40-80mg twice a day
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient HALOPERIDOL
Therapeutic Class BUTYROPHENES
Indications Symptomatic treatment of psychotic disorders.
Caution Extrapy ramidal side effects common but little drowsiness. May develop hypotension and cholinergic effects. Not approved in children less than 3yrs of age. C.f. prescribing in liver and renal disea More ...
Dose Range Adult: 0.5-5mg 2-3 times daily to a maximum of 30mg daily in divided doses. i.m: initially 2-10mg then every 4-8 hours according to response to total max. of 18mg daily. Pediatric 3-12 yrs: (15-
40kg) Initial dose: 0.25mg-0.5mg/day in 2-3 divided doses i
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CHLORDIAZEPOXIDE
Therapeutic Class PHENOTHIAZINES
Indications For short term relief of anxiety and tension in neuroses. Adjunct in
acute alcohol withdrawal. Also see Major Tranquliser on p.265.
Caution Dizziness, drowsiness, ataxia and slurred speech. Short term usage recommended because they are habit forming. Not recommended in children. C.f. prescribing in liver and renal disease p. 12; 25.
Dose Range Anxiety: 10mg 3 times daily increased if necessary to 60-100mg daily in divided doses. Alcohol withdrawal Syndrome: 25-100 mg repeated as needed after 2 to 4 hours, up to a maximum of 300 mg daily . Elderly: half adult dose.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CHLORPROMAZINE
Therapeutic Class PHENOTHIAZINES
Indications To control psychotic excitement.
Caution Drowsiness, precipitating confusional psychoses and postural hypotension with injections, nasal congestion and dry mouth. C.f. prescribing in liver and renal disease p. 12; 26.
Dose Range Oral: 75-300mg daily in divided doses. (But up to 1g may be given
in p sy choses). Inj: 25-50mg p er every 6-8 hours.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient FLUPHENAZINE
Therapeutic Class PHENOTHIAZINES
Indications Schizophrenia and other psychoses. Depot injections for ambulant
psychotics.
Caution Parkinsonian extrapy ramidal effects, drowsiness, hypotension.
Dose Range Adult: Tab: 2-10mg daily in divided doses. Inj: 12.5-100mg monthly.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient PERPHENAZINE
Therapeutic Class PHENOTHIAZINES
Indications Useful in paranoid states. [Schizop hrenia]
Caution Less drowsiness and hypotension. Less blood dycrasias of jaundice. See chlorp romazine. C.f. prescribing in liver and renal disease p.16; 34. Not recommended in children under 14yrs.
Dose Range Adult: 12-24mg daily in divided doses. Elderly: Use quarter-half of
adult dose.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient PROCHLORPERAZINE
Therapeutic Class PHENOTHIAZINES
Indications Minimum use in psychiatry . Antiemetic.
Caution c.f. prescribing in liver and renal disease p.17;35. See chlorpromazine.
Dose Range Psychiatry: 25-100mg daily in divided doses. Anti-emetic: 5-10mg
2-3 times daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient THIORIDAZINE
Therapeutic Class PHENOTHIAZINES
Indications When heavy sedation is not required. For restless, confused geriatric patients at night. Schizophrenia and other psychoses
Caution Causes less extrapy ramidal problems. Possibility of retinal pigmentation after prolonged usage and at doses over the maximum. More likely to induce hypotension. Contraindicated in cardiac disease. C More ...
Dose Range Adult: 150-300mg in 3 divided doses to a maximum of 800mg/day . Elderly: 30-100mg daily . Pediatric: 0.5mg/kg/day in divided doses to a maximum of 3mg/kg/day .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient TRIFLUOPERAZINE
Therapeutic Class PHENOTHIAZINES
Indications Paranoid and withdrawn states.
Caution Extrapy ramidal symptoms, ocular pigmentation. C.f. prescribing in liver and renal disease p. 18; 38. Safety and efficacy have not been established in children under 6yrs of age.
Dose Range Adult: 2- 5 mg twice daily, gradually increased to a usual range of
15-20 mg daily; in severe or resistant psychoses daily doses of
40 mg or more have been given. Pediatric under 12 yrs: Up to 5mg
once daily .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient FLUPENTHIXOL
Therapeutic Class THIOXANTHENES
Indications Maintenance in schizophrenia and other psychoses. Depot injection
for ambulant psychotics.
Caution Extrapy ramidal symptoms. Tardive dyskinesia; pregnancy . Pain may occur at injection site. C.f. Prescribing in liver and renal disease p. 13; 29.
Dose Range 20-40mg rep eated at 2-4 week intervals.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ZUCLOPENTHIXOL
Therapeutic Class THIOXANTHENES
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient ANTIDEPRESSANTS
Therapeutic Class ANTIDEPRESSANTS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient TRANQUILLIZERS
Therapeutic Class TRANQUILIZERS
Indications
Caution
Dose Range
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Pregnancy
Breast Feeding
Active Ingredient DOXAPRAM
Therapeutic Class RESPIRATORY-CEREBRAL STIMULANTS
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding