Formulary Monographs [CLOZAPINE, 28160804]

CLOZAPINE
ATYPICAL ANTIPSYCHOTICS
Schizophreniain patients unresponsive to, or intolerant of,
conventional antipsychotic drugs.
Anorexia; constipation; hypersalivation; malaise; speech disorders; urinary incontinence.
Adult:12.5 mg once or twice on the first day followed by 25 mg once or twice on the second day. Daily dosage may be increased gradually in step s of 25 to 50 mg. Maximum 900 mg per day . Adult 60 years and over: dose increments should be restricted to 2