Formulary Monographs [VERAPAMIL, 242892]

VERAPAMIL
CCBs, MISCELLANEOUS
Class IV antiarrhythmic.
Do not combine with beta blockers. Nausea, vomiting, hypotension. Avoid grapefruit juice. Concurrent use with caffeine may result in enhanced CNS stimulation. C.f. prescribing in liver disease p. 18.
Arrhythmias: 120-480mg 3-4 divided doses. Inj. 5-10mg slow i.v. over 2-3 minutes (preferably with ECG monitoring); Angina: 120mg
3 times daily or sustained release as 120-240mg once daily .
Verapamil crosses the placenta and can potentially cause fetal harm. Use during pregnancy only when the potential benefits justify the possible risks to the fetus.
Verapamil is distributed in breastmilk. Use is not recommended for lactating women.