Displaying 1 - 20 of 62
| Active Ingredient | VANCOMYCIN |
| Therapeutic Class | GLYCOPEPTIDES |
| Indications | Drug of choice for antibiotic - associated pseudomembranous colitis. Anaphylaxis and treatment of endocarditis and other sepsis caused by Gram-positive cocci. Effective in patients with methacillin More ... |
| Caution |
Hypotension, flushing, erythema, urticaria, pruritus, nausea, fever, chills. C.f. p rescribing in renal disease p . 38. Administration with other ototoxic or nephrotoxic drugs like aminoglycosides inc More ... |
| Dose Range |
Adult: 1g every 12 hours or 500mg every 6 hours. Pediatric: 10- 45mg/kg every 8-12 hours. |
| Drug Interactions | |
| Pregnancy | Manufacturer advises use only if potential benefit outweighs risk. Plasma-vancom More ... |
| Breast Feeding | Present in milk—significant absorption following oral administration unlikely. |
| Active Ingredient | ABSORBABLE GELATIN |
| Therapeutic Class | HEMOSTATICS |
| Indications | |
| Caution | |
| Dose Range | |
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| Pregnancy | |
| Breast Feeding |
| Active Ingredient | AMINOCAPROIC ACID |
| Therapeutic Class | HEMOSTATICS |
| Indications | Increase Fibrinolysis. |
| Caution | Allergic reactions, chills, fever. |
| Dose Range |
Initial priming dose 4-5g during the first hour, followed at 1 hour intervals of 1-1.25g. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | FACTOR IX |
| Therapeutic Class | HEMOSTATICS |
| Indications | Treatment of Hemophilia B. |
| Caution | Hypersensitivity reactions. |
| Dose Range | Depends on the desired increase in plasma IX levels. To calculate dose take body weight in kg multiplied by 1iu/kg multip lied by the desired increase in plasma factor IX. |
| Drug Interactions | |
| Pregnancy | Use only if clearly needed. |
| Breast Feeding |
| Active Ingredient | FACTOR VIII |
| Therapeutic Class | HEMOSTATICS |
| Indications | Treatment of Hemophilia A. |
| Caution | Some patients develop antibodies. |
| Dose Range |
The dosage of factor VIII should be determined for each patient and will vary with the circumstances involving bleeding. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | FIBRINOGEN HUMAN |
| Therapeutic Class | HEMOSTATICS |
| Indications | |
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| Dose Range | |
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| Pregnancy | |
| Breast Feeding |
| Active Ingredient | NALOXONE |
| Therapeutic Class | OPIATE ANTAGONISTS |
| Indications | Opioid Overdosage. |
| Caution | Beware physical dependence on narcotics. Has now replaced nalorphine as antagonist of choice. |
| Dose Range | 0.4-2mg i.v. repeated if necessary every 2-3 minutes to a maximum of 10mg. Pediatric: 10mcg/kg; if no response 100mcg/kg max.2mg. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ANTICONVULSANTS |
| Therapeutic Class | ANTICONVULSANTS |
| Indications | |
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| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PHENOBARBITAL |
| Therapeutic Class | BARBITURATES (ANTICONVULSANTS) |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PHENOBARBITONE |
| Therapeutic Class | BARBITURATES (ANTICONVULSANTS) |
| Indications | Grand mal and focal seizures. Less potent but easier to manage than phenytoin. |
| Caution | Avoid sudden withdrawal. Drowsiness, paradoxical excitement and restlessness in children and the elderly. Skin rashes . C.f. prescribing in liver and renal disease p. 16; 34. |
| Dose Range | 60 - 180mg at night in a single dose. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PRIMIDONE |
| Therapeutic Class | BARBITURATES (ANTICONVULSANTS) |
| Indications | As for phenytoin, but no longer recommended except for patients already well controlled with it. |
| Caution | Avoid sudden withdrawal. Drowsiness, ataxia, nausea, rashes and folate deficiency. May decrease effectiveness of pill, may cause drowsiness and loss of appetite. Avoid alcohol. C.f. prescribing in li More ... |
| Dose Range | Adult and children 10 years and over: 125mg at bedtime increased if necessary by 125mg every 3 days to a total of 500mg daily in divided doses. The daily dose may be increased further every 3 days by 250 mg up to a maximum of 1.5 g daily given in divided |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CLONAZEPAM |
| Therapeutic Class | BENZODIAZEPINES (ANTICONVULSANTS) |
| Indications | All forms of epilepsy including status epilepticus. |
| Caution | Withdraw drug slowly. Avoid alcohol. Drowsiness limits chronic use. |
| Dose Range | 1 mg (500 mcg in the elderly) at night for 4 nights gradually increased over 2 to 4 weeks to a usual maintenance dose of 4 to 8mg daily ;maximum of 20mg/day in divided doses. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PHENYTOIN |
| Therapeutic Class | HYDANTOINS |
| Indications | Partial and generalized tonic-clonic seizures. Prophylaxis after cerebral trauma or neuro-surgery . |
| Caution |
Avoid sudden withdrawal. Do not use substitute products. Monitor drug levels when in doubt. Nystagmus, dizziness, ataxia, slurred speech, drowsiness, blurred vision and confusion. Hirsutism, gingival More ... |
| Dose Range |
Adult:150-300mg daily, rarely more than 400mg, in one (night time) or two doses daily to a maximum of 600mg daily as a single dose or as 2 divided doses. In status epilepticus loading doses of 10-20 mg/kg given by slow infusion according to body weight, f |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ETHOSUXIMIDE |
| Therapeutic Class | SUCCINIMIDES |
| Indications |
Absence seizures, (petit mal). Note: Petit mal does not begin in adulthood. |
| Caution |
Avoid sudden withdrawal. Dizziness, ataxia, G.I. upset anorexia, hiccups, headache. Take with food or milk to reduce gastric irritation. |
| Dose Range | Adult and children over 6 years: 500mg-2g daily in divided doses. Paediatric: 250 mg initially, increased gradually to 20 mg/kg per day; (maximum 1g daily). |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CARBAMAZEPINE |
| Therapeutic Class | ANTICONVULSANTS MISCELLANEOUS |
| Indications |
Grand mal (tonic clonic), partial (focal) and complex partial Psychomotor or temporal lobe seizures. Drug of choice. Trigeminal neuralgia. |
| Caution |
Withdraw drug slowly. Drug increases hepatic microsomal enzymes - increases warfarin metabolism, nausea, drowsiness, dizziness, Unsteadiness, rash in 3% patients. Occasional jaundice and (rare) leucop More ... |
| Dose Range |
Adult: Epilepsy: 100-200mg 2 times daily, increasing as necessary to 800-1200 mg/day daily in divided doses with food. CNS side effects are dose limiting. Trigeminal Neuralgia: 100mg 2 times daily. Child 1 month-12yrs: Initially 5mg/kg at night or 2.5mg/k |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CARBAMAZEPINE CR |
| Therapeutic Class | ANTICONVULSANTS MISCELLANEOUS |
| Indications | Grand mal (tonic clonic), partial (focal) and complex partial psychomotor or temporal lobe seizures. Drug of choice. Trigeminalneuralgia. |
| Caution | Withdraw drug slowly. Drug increases hepatic microsomal enzymes - increases warfarin metabolism, nausea, drowsiness, dizziness, Unsteadiness, rash in 3% patients. Occasional jaundice and (rare) leucop More ... |
| Dose Range |
Adult: Epilepsy: 100-200mg 2 times daily, increasing as necessary to 800-1200 mg/day daily in divided doses with food. CNS side effects are dose limiting. Trigeminal Neuralgia: 100mg 2 times daily. Child 1 month-12yrs: Initially 5mg/kg at night or 2.5mg/k |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GABAPENTIN |
| Therapeutic Class | ANTICONVULSANTS MISCELLANEOUS |
| Indications | Partial seizure, adjunct postherpetic neuralgia, diabetic peripheral neuropathy, and neuropathic pain |
| Caution | Peripheral edema, myalgia, ataxia, dizziness, hyperactive behavior, nystagmus, somnolence, tremor, disorder of form of thought, hostile behavior, mood swings, fatigue, stevens-johnson syndrome (rare), More ... |
| Dose Range |
Adult and children over 12 years: Epilepsy: Initial dose of 300 mg on the first day of treatment, 300 mg twice daily on the second day, and 300 mg three times daily on the third day ; alternatively , gabapentin may be given as 300 mg thr |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | LAMOTRIGINE |
| Therapeutic Class | ANTICONVULSANTS MISCELLANEOUS |
| Indications |
Monotherapy or adjunctive treatment of partial seizures; primary and secondary generalised tonic-clonic seizures and seizures associated with Lennox-Gastaut syndrome. To be used in women of child-bear More ... |
| Caution | Blurred vision; aggression; agitation; arthralgia; ataxia; back pain; diarrhoea; diplopia; dizziness; drowsiness; dry mouth; headache; insomnia; nausea; nystagmus; rash; tremor; vomiting. |
| Dose Range |
Adult and children 12 years and older: monotherapy: 25 mg once daily for 2 weeks followed by 50 mg once daily for 2 weeks; increased by a maximum of 50 to 100 mg every 1 to 2 weeks to usual maintenance doses of 100 to 200 mg daily, given as a sin |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | LEVETIRACETAM |
| Therapeutic Class | ANTICONVULSANTS MISCELLANEOUS |
| Indications | Epilepsy . |
| Caution | Somnolence, weakness, and dizziness, depression, nervousness. |
| Dose Range | Adult: Monotherapy: 500mg daily increased by 500mg increments every 2 weeks. Maximum dose 3g daily in divided doses. Adjunct therapy: 1g on first day of treatment, increased by 1g increments every 2-4 weeks. Maximum dose 3g daily in divided doses. Chil |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | MAGNESIUM SULPHATE |
| Therapeutic Class | ANTICONVULSANTS MISCELLANEOUS |
| Indications | Eclampsia and pre-eclampsia. |
| Caution | c.f. prescribing in liver and renal disease p. 15; 31. |
| Dose Range | Loading dose 4g over 5 to 15 minutes, followed 1g per hour (for at least 24 hours after the last seizure). |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |