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PHENYTOIN
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HYDANTOINS
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Partial and generalized tonic-clonic seizures. Prophylaxis after cerebral trauma or neuro-surgery .
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Avoid sudden withdrawal. Do not use substitute products. Monitor
drug levels when in doubt. Nystagmus, dizziness, ataxia, slurred speech, drowsiness, blurred vision and confusion. Hirsutism, gingival hypertrophy. May decrease effectiveness of birth control pill. Avoid alcohol use. (Products are not inter-changeble) c.f. prescribing in liver disease p. 16. |
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Adult:150-300mg daily, rarely more than 400mg, in one (night time)
or two doses daily to a maximum of 600mg daily as a single dose or as 2 divided doses. In status epilepticus loading doses of 10-20 mg/kg given by slow infusion according to body weight, f |
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