Displaying 1 - 9 of 9
| Active Ingredient | SULFAMETHOXAZOLE | TRIMETHOPRIM |
| Therapeutic Class | SULPHONAMIDES |
| Indications | Urinary tract infections; typhoid, invasive Salmonellosis; H. influenzae. Infections, exacerbations of chronic bronchitis. |
| Caution | Discontinue if skin rash develops. Nausea and vomiting may occur. Sensitivity to sunlight increases while taking this medication. Use a sunscreen when outdoors. C.f. prescribing in renal disease p. More ... |
| Dose Range |
Adult: 1-2 tablets every 8-12 hours. Pediatric: 6 weeks - 5 months: ½ teaspoonful every 12 hours. 6 months - 5 years: 1 teaspoonful every 12 hours. 6-12 years: 2 teaspoonsful every 12 hours. Take with a full glass of water and drink several glasses of wat |
| Drug Interactions | |
| Pregnancy | Co-trimoxazole crosses the placenta and may interfere with folic acid metabolism More ... |
| Breast Feeding | Co-trimoxazole is distributed into milk with small risk of kernicterus in jaundi More ... |
| Active Ingredient | SULPHASALAZINE |
| Therapeutic Class | SULPHONAMIDES |
| Indications | Inflammatory bowel disease. |
| Caution | Yellow-orange discoloration of skin, urine and other body fluids. Increased sensitivity to sunlight. Do not take if allergic to sulfa-drugs, aspirin or other salicyclates. Take with food to avoid stom More ... |
| Dose Range | Adult: 1-2g 4 times daily. Maintenance: 500mg 4 times a day. Pediatric: 2 years and older: 40-60mg/kg daily. Maintenance: 20-30mg/kg daily . |
| Drug Interactions | |
| Pregnancy |
Theoretical risk of neonatal haemolysis in third trimester; adequate folate supp More ... |
| Breast Feeding |
Small amounts in milk (1 report of bloody diarrhoea); theoretical risk of neonat More ... |
| Active Ingredient | DOXYCYCLINE |
| Therapeutic Class | TETRACYCLINES |
| Indications | Exacerbations of chronic bronchitis, brucella, chlamydial infections, my coplasma, acne vulgaris (Low dose), rickettsia. Urinary tract infections (local alternative). |
| Caution | Hepatic impairment. Avoid excess exposure to sunlight. C.f. prescribing in liver and renal disease p. 13; 28. |
| Dose Range |
200mg on the first day (as a single dose or in divided doses), then 100mg daily. In severe infections the initial dosage is maintained throughout the course of treatment. See BDS supply protocols pg. 3. |
| Drug Interactions | |
| Pregnancy | Avoid in pregnant women. Administration during the second or third trimester may More ... |
| Breast Feeding |
Tetracyclines are excreted in breastmilk and cross the placenta. Consequently th More ... |
| Active Ingredient | MINOCYCLINE |
| Therapeutic Class | TETRACYCLINES |
| Indications | Meningococcal carriers. Active against N. Meningitidis, some Methicillin Resistant Staph & H. Influenzae. Urinary and respiratory tract infections, acne and skin and soft tissue infections. |
| Caution | G.I upset, vestibular dysfunction, headache, localized pigmentary disturbances.Not to be used in children under 8 years. C.f. prescribing in liver and renal disease p. 15; 32. |
| Dose Range | Adult and Children 12 years and over: 200mg followed by 100mg every 12 hours. Do not exceed 400mg in 24 hours. See BDS supply protocols pg. 3. |
| Drug Interactions | |
| Pregnancy | Avoid in pregnant women. Administration during the second or third trimester may More ... |
| Breast Feeding |
Tetracyclines are excreted in breastmilk and cross the placenta. Consequently th More ... |
| Active Ingredient | TETRACYCLINE |
| Therapeutic Class | TETRACYCLINES |
| Indications | Exacerbations of chronic bronchitis, urninary tract infections, prostatitis, travellers’ diarrhoea, brucella, chlamydia, mycoplasma, rickettsia, acne vulgaris (low dose). Pleural effusions due to mali More ... |
| Caution | Drug sensitivity, tooth discoloration, nausea, vomiting, epigastric burning, photosenitivity, vaginal candidiasis, diarrhoea. Renal or hepatic impairment. Not recommended in children under 12 years ol More ... |
| Dose Range |
Adult and Children 12 years and over: 250-500mg every 6 hours. See BDS supply protocols pg. 3. |
| Drug Interactions | Antacids, milk, oral iron (chelates and reduces absorption) |
| Pregnancy | Avoid in pregnant women; effects on skeletal development have been documented in More ... |
| Breast Feeding | Should not be given to women who are breast-feeding (although absorption and the More ... |
| Active Ingredient | VANCOMYCIN |
| Therapeutic Class | GLYCOPEPTIDES |
| Indications | Drug of choice for antibiotic - associated pseudomembranous colitis. Anaphylaxis and treatment of endocarditis and other sepsis caused by Gram-positive cocci. Effective in patients with methacillin More ... |
| Caution |
Hypotension, flushing, erythema, urticaria, pruritus, nausea, fever, chills. C.f. p rescribing in renal disease p . 38. Administration with other ototoxic or nephrotoxic drugs like aminoglycosides inc More ... |
| Dose Range |
Adult: 1g every 12 hours or 500mg every 6 hours. Pediatric: 10- 45mg/kg every 8-12 hours. |
| Drug Interactions | |
| Pregnancy | Manufacturer advises use only if potential benefit outweighs risk. Plasma-vancom More ... |
| Breast Feeding | Present in milk—significant absorption following oral administration unlikely. |
| Active Ingredient | CLINDAMYCIN HYDROCHLORIDE |
| Therapeutic Class | LINCOMYCINS |
| Indications | Staphylococcal bone or joint sepsis, peritonitis (alternative to gentamicin and metronidazole). Effective againstmany anaerobes. Bacteroides fragilis. Gram-positive cocci including penicillin-resis More ... |
| Caution | Diarrhoea pseudomembranous colitis. This is the commonest antibiotic causing it (responds to oral metronidazole or vancomycin). Report any excess diarrhoea, do not take anti-diarrhoeal drugs. C.f. pre More ... |
| Dose Range | Adult: 150-450mg every 6 hours. Pediatricunder 12 years: 3-6 mg/kg/day every 6 hours. See BDS supply protocols pg. 3. |
| Drug Interactions | |
| Pregnancy | Not known to be harmful. |
| Breast Feeding | Clindamycin has the potential to cause adverse effects on the breastfed infant's More ... |
| Active Ingredient | CLINDAMYCIN PHOSPHATE |
| Therapeutic Class | LINCOMYCINS |
| Indications | Staphylococcal bone or joint sepsis, peritonitis (alternative to gentamicin and metronidazole). Effective against many anaerobes. Bacteroides fragilis. Gram-positive cocci including penicillin-resista More ... |
| Caution | Diarrhoea, pseudomembranous colitis. This is the commonest antibiotic causing it (responds to oral metronidazole or vancomycin). Report any excess diarrhoea, do not take anti-diarrhoeal drugs. |
| Dose Range | Adult: 150-450mg every 6 hours. Pediatricunder12 years: 3-6 mg/kg/day every 6 hours. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ETHOSUXIMIDE |
| Therapeutic Class | SUCCINIMIDES |
| Indications |
Absence seizures, (petit mal). Note: Petit mal does not begin in adulthood. |
| Caution |
Avoid sudden withdrawal. Dizziness, ataxia, G.I. upset anorexia, hiccups, headache. Take with food or milk to reduce gastric irritation. |
| Dose Range | Adult and children over 6 years: 500mg-2g daily in divided doses. Paediatric: 250 mg initially, increased gradually to 20 mg/kg per day; (maximum 1g daily). |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |