Formulary Monographs [DOXYCYCLINE, 081224]
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DOXYCYCLINE
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TETRACYCLINES
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Exacerbations of chronic bronchitis, brucella, chlamydial infections, my coplasma, acne vulgaris (Low dose), rickettsia. Urinary tract infections (local alternative).
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Hepatic impairment. Avoid excess exposure to sunlight. C.f. prescribing in liver and renal disease p. 13; 28.
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200mg on the first day (as a single dose or in divided doses), then
100mg daily. In severe infections the initial dosage is maintained throughout the course of treatment. See BDS supply protocols pg. 3. |
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Avoid in pregnant women. Administration during the second or third trimester may cause discoloration of the child’s teeth, and maternal hepatotoxicity has been reported with large parenteral doses.
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Tetracyclines are excreted in breastmilk and cross the
placenta. Consequently they chelate with calcium in the fetus and infant leading to damage to growing bones & teeth. |
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