Displaying 1 - 20 of 37
| Active Ingredient | PROTAMINE SULPHATE |
| Therapeutic Class | ANTIHEPARIN |
| Indications | Treatment of heparin overdose.. |
| Caution |
Flushing, hypotension, bradycardia. Protamine sulfate is a weak anticoagulant and e +xcess amounts may worsen or trigger bleeding episodes. |
| Dose Range | 1mg neutralises 100 units of heparin when given within 15 minutes. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | AMLODIPINE |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | Hypertension, chronic stable angina, vasospastic angina. |
| Caution |
Headache, peripheraledema, dizziness, flushing, tender or bleeding gums, rash. Avoid grapefruit juice. |
| Dose Range | 2.5mg-10mg daily. Dose reductions may be indicated in the elderly or those with hepatic failure, but not necessary in renal impairment. |
| Drug Interactions | |
| Pregnancy | Use in pregnancy only when clearly needed and when the benefits outweigh the pot More ... |
| Breast Feeding |
| Active Ingredient | NIFEDIPINE |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | Angina pectoris when a vasospastic element is present, hypertension. Raynaud's disease. |
| Caution | Avoid the use of diuretics. Headache, flushing, dizziness. Avoid grapefruit juice. Concurrent use may cause severe muscle tenderness and pain..c.f. prescribing in liver and renal p. 15; 33. |
| Dose Range | 20mg twice daily increased if necessary to 40mg twice daily . |
| Drug Interactions | |
| Pregnancy | Nifedipine may inhibit labour. Use during pregnancy only when the potential bene More ... |
| Breast Feeding | Nifedipine is distributed in breastmilk. Use with caution in lactating. |
| Active Ingredient | NIMODIPINE |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | Subarachnoid hemorrhage. |
| Caution | Weight loss, cardiac arrythmias, headache, depression, tinnitus. |
| Dose Range | 60mg every four hours started within 4 days for twenty -one days. |
| Drug Interactions | |
| Pregnancy | Nimodipine should be used during pregnancy only when the potential benefits just More ... |
| Breast Feeding | Nimodipine is distributed in breastmilk. Use with caution in lactating women. |
| Active Ingredient | IDARUCIZUMAB |
| Therapeutic Class | ANTIDOTAL AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GENERAL ANAESTHETICS |
| Therapeutic Class | GENERAL ANESTHETICS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | THIOPENTONE SODIUM |
| Therapeutic Class | BARBITURATES (ANAESTHETICS) |
| Indications | Induction of general anaesthesia; anaesthesia of short duration. |
| Caution | Induction: 50-100mg intermittently every 30-40 seconds or as a single dose 3-5 mg/kg injection. |
| Dose Range | c.f. prescribing in liver disease p. 18. |
| Drug Interactions | |
| Pregnancy | May depress neonatal respiration when used during delivery. |
| Breast Feeding | Breast-feeding can be resumed as soon as mother has recovered sufficiently from More ... |
| Active Ingredient | DESFLURANE |
| Therapeutic Class | INHALATION ANAESTHETICS |
| Indications | Maintenance of general anaesthesia. |
| Caution | Respiratory depression, hypotension, and arrhythmias may occur. |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ISOFLURANE |
| Therapeutic Class | INHALATION ANAESTHETICS |
| Indications | General Anaesthetic. |
| Caution | Isoflurane potentiates all commonly used muscle relaxants; therefore less than usual amounts of such agents are recommended. |
| Dose Range | Induction: 0.5-3% in oxygen or nitrous oxide-oxygen. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SEVOFLURANE |
| Therapeutic Class | INHALATION ANAESTHETICS |
| Indications | Anaesthesia. |
| Caution | Hypotension, liver failure, respiratory depression, seizure. |
| Dose Range | Adult or Paediatric: 0.5-3% concentration with or without concomitant use of nitrous oxide. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | KETAMINE |
| Therapeutic Class | GENERAL ANAESTHETICS MISCELLANEOUS |
| Indications | Anaesthetic and analgesic. |
| Caution | See p. 260. induction of dissociative anesthesia. |
| Dose Range | 1-4.5mg/kg intravenously or 6.5-13mg/kg intramuscularly . S edation and analgesia: 2-4mg/kg I.m or 0.2-0.75mg/kg IV. |
| Drug Interactions | |
| Pregnancy | May depress neonatal respiration if used during delivery. |
| Breast Feeding | Avoid for at least 12 hours after last dose. |
| Active Ingredient | PROPOFOL |
| Therapeutic Class | GENERAL ANAESTHETICS MISCELLANEOUS |
| Indications | Induction and maintenance of general anaesthesia |
| Caution | Pain at injection site; apnea; hypotension. |
| Dose Range | Adult: Induction dose is 2-2.5mg/kg. Maintenance: 6-12mg/kg/hour. Dose adjustments are required in the elderly . |
| Drug Interactions | |
| Pregnancy | Propofol should only be used in pregnancy if clearly needed. Propofol is not rec More ... |
| Breast Feeding | Breast-feeding can be resumed as soon as mother has recovered sufficiently from More ... |
| Active Ingredient | ANALGESICS - ANTIPYRETICS |
| Therapeutic Class | ANALGESICS-ANTIPYRETICS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CELECOXIB |
| Therapeutic Class | CYCLOOXYGENASE-2 (COX2) INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ETORICOXIB |
| Therapeutic Class | CYCLOOXYGENASE-2 (COX2) INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | MELOXICAM |
| Therapeutic Class | CYCLOOXYGENASE-2 (COX2) INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ASPIRIN |
| Therapeutic Class | SALICYLATES |
| Indications | Mild to moderate pain and fever, myocardial and stroke. |
| Caution | May cause G.I. bleeding, irritation, rashes, bronchospasm, nasal polyps. Contraindicated with G.I. ulceration, anticoagulants, bleeding disorders, gout and in children and adolescents with viral ill More ... |
| Dose Range | 300-900mg every 4-6 hours as necessary. Usual maximum 4g daily. Soluble or E.C. may be best for chronic use. See BDS supply protocols pg. 4 for maximum reimbursable quantities. |
| Drug Interactions | |
| Pregnancy | Use antiplatelet doses with caution during third trimester; impaired platelet fu More ... |
| Breast Feeding | Aspirin is distributed in breastmilk. Use with caution in lactating women. |
| Active Ingredient | DICLOFENAC POTASSIUM |
| Therapeutic Class | OTHER NONSTEROIDAL ANTI-INFLAMMATORY AGENTS |
| Indications | Short term treatment of mild to moderate pain where rapid onset of action is desired. Not supplied for chronic anti-inflammatory conditions. |
| Caution | Under Diclofenac Sodium. |
| Dose Range |
Adult: 25-50mg three times daily. Usually no more than a 5 day supply is needed. Primary dysmenorrhoea: 100mg initially, then 50mg 3 times daily to a maximum of 150mg daily. Children 1 year and over: 0.25-1ml/kg body weight daily depending on the sever |
| Drug Interactions | |
| Pregnancy | Avoid unless the potential benefit outweighs the risk. |
| Breast Feeding | Diclofenac is distributed in breastmilk and is not recommended in lactating wome More ... |
| Active Ingredient | DICLOFENAC SODIUM |
| Therapeutic Class | OTHER NONSTEROIDAL ANTI-INFLAMMATORY AGENTS |
| Indications | Pain and inflammation in rheumatic disorders in patients intolerant or resistant to aspirin and indomethacin. |
| Caution | G.I. irritation; allergic disorders (as for asp irin) but less frequent. c.f. prescribing in liver and renal disease p. 13; 28. |
| Dose Range |
Adult: 25-50mg every 6-8 hours or 75-150 mg in divided doses, or 100mg daily as a single dose using the Retard preparation. Take with food.Inj.: I.M. 25-50mg every 6-8 hours. Supp: 50mg at night or every 6-8 hours if tablets are not tolerated. See BDS sup |
| Drug Interactions | |
| Pregnancy | Avoid unless the potential benefit outweighs the risk. |
| Breast Feeding | Diclofenac is distributed in breastmilk and is not recommended in lactating wome More ... |
| Active Ingredient | IBUPROFEN |
| Therapeutic Class | OTHER NONSTEROIDAL ANTI-INFLAMMATORY AGENTS |
| Indications |
Mild to moderate pain. Alternative to aspirin or indomethacin, with less side effects. |
| Caution | G.I. irritation; allergic disorders (as for aspirin) but less frequent. May administer with meals or milk if G.I. upset occurs. C.f. prescribing in liver and renal disease p. 14; 31. |
| Dose Range | Adult: 400mg 3-4 times daily. Do not exceed 2400mg total daily dose. Pediatric: 4-10mg/kg every 6-8 hours to a maximum of 40mg/kg/day. See BDS supply protocols pg. 5. |
| Drug Interactions | |
| Pregnancy | Avoid unless the potential benefit outweighs the risk. |
| Breast Feeding | Ibuprofen is distributed in breastmilk. Use with caution in lactating women. |