Formulary Monographs [KETAMINE, 280492]
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KETAMINE
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GENERAL ANAESTHETICS MISCELLANEOUS
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Anaesthetic and analgesic.
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See p. 260. induction of dissociative anesthesia.
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1-4.5mg/kg intravenously or 6.5-13mg/kg intramuscularly . S edation and analgesia: 2-4mg/kg I.m or 0.2-0.75mg/kg IV.
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May depress neonatal respiration if used during delivery.
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Avoid for at least 12 hours after last dose.
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Colourless liquid, light sensitive. Used as an intravenous or intramuscular anaesthesia. Used as induction agent in patients with low cardiac output states not due to primary my ocardial failure.
Sole agent in patients in whom the upper airway may be relatively inaccessible i.e. severe burns or trauma. In very low doses as a highly potent supplement during generalanaesthesia using other agents. Main side effect due to production of hallucinations as part of emergence phenomena. This may be reduced by the use of a powerful sedative e.g. diazepam. Momentarily rise in blood pressure problems in hypertensive patients. Use of drug is contraindicated (relative only ) in patients with psychiatric history and patients with uncontrolled hypertension. |