Displaying 1 - 20 of 57
| Active Ingredient | GENTAMICIN |
| Therapeutic Class | AMINOGLYCOSIDES |
| Indications | Septicaemia and neonatal sepsis, biliary infections, intraabdominal and UTI, acute pyelonephritis. Severe gram-negative infections, primarily pseudomonas infections. |
| Caution | Increase dose interval in renal impairment in children and the elderly. Use nomogram (see renal disease guidelines p.19-38) and check peak (1 hour) and trough (predose) levels. Nehrotoxicity or ototo More ... |
| Dose Range |
i.m. 3-5mg/kg/day in divided doses every 8 hours for 7-10 days. 12 hours (clearance 30-70 ml/min), 24 hours (clearance 10-30ml/min, 48 hours (clearance 5-10ml/min) |
| Drug Interactions | |
| Pregnancy | Risk of auditory or vestibular nerve damage in the infant when aminoglycosides a More ... |
| Breast Feeding |
| Active Ingredient | TOBRAMYCIN |
| Therapeutic Class | AMINOGLYCOSIDES |
| Indications | Septicaemia and neonatal sepsis, biliary infections, endocarditis, acute pyelonephritis. Tobramycin is slightly more effective for Pseudomonas aeruginosa than gentamicin, but shows less activity agai More ... |
| Caution | Nephrotoxicity and ototoxicity occur with high concentrations. It is less toxic than gentamicin. The dose should be reduced in renal failure and in the elderly. C.f. prescribing in renal disease p. 3 More ... |
| Dose Range |
Adult: 3-5mg/kg/day divided every 8 to 12 hours based on renal function and serum tobramy cin levels: or once-daily administration is 4-7mg/kg/day; higher doses may be needed depending on the diagnosis. Pediatric 1 mth- 12 yrs: 2-2.5mg/kg every 8 hours. |
| Drug Interactions | |
| Pregnancy | Risk of auditory or vestibular nerve damage in the infant when aminoglycosides a More ... |
| Breast Feeding |
| Active Ingredient | CEFADROXIL |
| Therapeutic Class | FIRST GEN CEPHALOSPORINS |
| Indications | Oral cefadroxil is used for the treatment of pharyngitis and tonsillitis caused by Streptococcus pyogenes. Inactive against Pseudomonas and Bacteroides. |
| Caution | Nausea and vomiting, hypersensitivity in about 10% of penicillin sensitive patients otherwise little toxicity. Note high cost of cephalosporins. Best used for specifically identified susceptible o More ... |
| Dose Range | Adult: 1-2g daily as a single dose or in two divided doses. Pediatric: Under 1 year: 25mg/kg in divided doses; 1-6 years: 250mg twice daily; over 6 years: 500mg twice a day. See BDS supply protocols pg.3. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Present in milk in low concentration, but appropriate to use. |
| Active Ingredient | CEFAZOLIN |
| Therapeutic Class | FIRST GEN CEPHALOSPORINS |
| Indications | Infections due to susceptible Gram-positive and Gram-negative bacteria. |
| Caution |
Anorexia, Diarrhea , Eosinophilia , Fever ,Increased transaminases Leukopenia ,Nausea and vomiting ,Neutropenia ,Oral candidiasis,Pain at injection site ,Phlebitis |
| Dose Range |
Adult: 500mg-1g every 8 hours with up to 1-1.5g every 6 hours in severe infections. Pediatric: 25-50mg/kg/day in 3-4 doses up to 100mg/kg/day . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CEPHRADINE |
| Therapeutic Class | FIRST GEN CEPHALOSPORINS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CEFUROXIME |
| Therapeutic Class | SECOND GEN CEPHALOSPORINS |
| Indications | Infections caused by susceptible Gram-positive and Gram-negative bacteria, including infections of the bones and joints, CNS, skin and skin structures, respiratory tract, genito-urinary tract (includi More ... |
| Caution | Gastrointestinal disturbances, including diarrhoea, nausea, and vomiting. Mild to moderate hearing loss has been reported in some children given cefuroxime for the treatment of meningitis. |
| Dose Range | Adult and children 12 years and over: 250 mg twice daily dose may be doubled in severe lower respiratory tract infections or if pneumonia is suspected; Pediatric: 3 months–2 years; 10 mg/kg twice daily (max. p er dose 125 mg). 2–11 years; 15 mg/kg twice |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Present in milk in low concentration, but appropriate to use. |
| Active Ingredient | CEFIXIME |
| Therapeutic Class | THIRD GEN CEPHALOSPORINS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CEFOTAXIME |
| Therapeutic Class | THIRD GEN CEPHALOSPORINS |
| Indications | Infections due to susceptible Gram-positive and Gram-negative bacteria, surgical infection prophylaxis, uncomplicated gonorrhea. |
| Caution | Colitis ,Diarrhea ,Elevated blood urea nitrogen (BUN) and creatinine ,Elevated hepatic transaminases ,Eosinophilia ,Fever ,Injection site pain , Nausea ,Pruritus ,Rash |
| Dose Range |
Adult: 1g every 12 hours. gonorrhoea; 500mg i.m. Pediatric: Child 1 month–11 years: 50mg/kg every 12 hours; Child 12–17 years; 1g every 12 hours. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Present in milk in low concentration, but appropriate to use. |
| Active Ingredient | CEFTAZIDIME |
| Therapeutic Class | THIRD GEN CEPHALOSPORINS |
| Indications | Infections caused by susceptible Gram-positive and Gram-negative bacteria, especially infections due to Pseudomonas spp . |
| Caution | Transient increases in transaminases, eosinophilia, diarrhea, immune hypersensitivity reaction, phlebitis, rash (maculopapular or erythematous), thrombocytosis, injection site pain, abdominal pain |
| Dose Range | Adult:1g every 8-12 hours. Maximum 6g daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Present in milk in low concentration, but appropriate to use. |
| Active Ingredient | CEFTRIAXONE |
| Therapeutic Class | THIRD GEN CEPHALOSPORINS |
| Indications | As for Cephadroxil |
| Caution | As for Cephadroxil |
| Dose Range | 1-2g once daily or in two divided doses. Maxiumum 4g daily. |
| Drug Interactions | |
| Pregnancy | Specialist sources indicate suitable for use in pregnancy. |
| Breast Feeding | Present in milk in low concentration, but appropriate to use. |
| Active Ingredient | CEFEPIME |
| Therapeutic Class | FOURTH GEN CEPHALOSPORINS |
| Indications | Infections due to susceptible Gram-positive and Gram-negative bacteria, including those of the abdomen, urinary tract, respiratory tract, and skin and skin structures. Effective against Pseudomonas a More ... |
| Caution | Hypersensitivity reactions. |
| Dose Range | Adult: 1 to 2g daily in 2 divided doses for mild to moderate infections, increased to 4g daily in 2 divided doses in severe infections. Maximum 6g daily. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Cefepime is distributed into milk in low concentrations following parenteral adm More ... |
| Active Ingredient | CILASTATIN | IMIPENEM |
| Therapeutic Class | CARBAPENEMS |
| Indications |
Aerobic and anaerobic Gram-positive and Gram-negative infections; (not indicated for CNS infections) hospital-acquired septicaemia. |
| Caution |
Diarrhoea; eosinophilia; nausea (may reduce rate of infusion); rash; vomiting |
| Dose Range | Adult: 500mg every 6 hours, alternatively 1g every 8 hours. |
| Drug Interactions | |
| Pregnancy | Manufacturer advises avoid unless potential benefit outweighs risk. Both imipene More ... |
| Breast Feeding | Present in milk but unlikely to be absorbed. |
| Active Ingredient | ERTAPENEM |
| Therapeutic Class | CARBAPENEMS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | MEROPENEM |
| Therapeutic Class | CARBAPENEMS |
| Indications | Indicated as a single agent therapy for the treatment of complicated skin and skin structure infections due to Staphylococcus aureus (methicillin-susceptible isolates only),Pseudomonas aeruginosa, Esc More ... |
| Caution |
Abdominal pain; diarrhoea; disturbances in liver function tests; headache; nausea; pruritus; rash; thrombocy thaemia; vomiting. |
| Dose Range | Adult: 0.5-1g every 8 hours |
| Drug Interactions | |
| Pregnancy | There are insufficient human data to establish whether there is a drug-associate More ... |
| Breast Feeding | Drug has been reported to be excreted in human milk; no information is available More ... |
| Active Ingredient | ERYTHROMYCIN BASE |
| Therapeutic Class | ERYTHROMYCINS |
| Indications | Infections caused by most gram positive bacteria with limited usefulness in staphylococcal infections. Alternative to penicillin in hypertensive patients. Drug of choice for Legionnaires di More ... |
| Caution | Nausea, vomiting, abdominal cramps. C.f prescribing on liver and renal disease. P. 13 |
| Dose Range |
Adult: Stearate/Base: 250-500mg every 6 hours or 500mg every 12 hours to a maximum of 4g per day. May Take with food to lessen stomach upset. Injection15-2-mg /kg/day up to 4g/day. Pediatric: 1 month-2 years: 125mg four times a day; 2-8 years: 250mg f |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Only small amounts in milk—not known to be harmful. |
| Active Ingredient | ERYTHROMYCIN ESTOLATE |
| Therapeutic Class | ERYTHROMYCINS |
| Indications | Infections caused by most gram positive bacteria with limited usefulness in staphylococcal infections. Alternative to penicillin in hypertensive patients. Drug of choice for Legionnaires di More ... |
| Caution | Nausea, vomiting, abdominal cramps. C.f prescribing on liver and renal disease. P. 13 |
| Dose Range | Adult: Stearate/Base: 250-500mg every 6 hours or 500mg every 12 hours to a maximum of 4g per day. May Take with food to lessen stomach upset. Injection15-2-mg /kg/day up to 4g/day. Pediatric: 1 month-2 years: 125mg four times a day; 2-8 years: 250mg four |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ERYTHROMYCIN ETHYLSUCCINATE |
| Therapeutic Class | ERYTHROMYCINS |
| Indications | Infections caused by most gram positive bacteria with limited usefulness in staphylococcal infections. Alternative to penicillin in hypertensive patients. Drug of choice for Legionnaires disease. Chla More ... |
| Caution | Nausea, vomiting, abdominal cramps |
| Dose Range | Adult: Stearate/Base: 250-500mg every 6 hours or 500mg every 12 hours to a maximum of 4g per day. May Take with food to lessen stomach upset. Injection15-2-mg /kg/day up to 4g/day. Pediatric: 1 month-2 years: 125mg four times a day; 2-8 years: 250mg four |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ERYTHROMYCIN LACTOBIONATE |
| Therapeutic Class | ERYTHROMYCINS |
| Indications | Infections caused by most gram positive bacteria with limited usefulness in staphylococcal infections. Alternative to penicillin in hypertensive patients. Drug of choice for Legionnaires disease. Chla More ... |
| Caution | Nausea, vomiting, abdominal cramps |
| Dose Range | Adult: Stearate/Base: 250-500mg every 6 hours or 500mg every 12 hours to a maximum of 4g per day. May Take with food to lessen stomach upset. Injection15-2-mg /kg/day up to 4g/day. Pediatric: 1 month-2 years: 125mg four times a day; 2-8 years: 250mg four |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ERYTHROMYCIN STEARATE |
| Therapeutic Class | ERYTHROMYCINS |
| Indications | Infections caused by most gram positive bacteria with limited usefulness in staphylococcal infections. Alternative to penicillin in hypertensive patients. Drug of choice for Legionnaires disease. Chla More ... |
| Caution | Nausea, vomiting, abdominal cramps |
| Dose Range | Adult: Stearate/Base: 250-500mg every 6 hours or 500mg every 12 hours to a maximum of 4g per day. May Take with food to lessen stomach upset. Injection15-2-mg /kg/day up to 4g/day. Pediatric: 1 month-2 years: 125mg four times a day; 2-8 years: 250mg four |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | AUTONOMIC DRUGS |
| Therapeutic Class | AUTONOMIC DRUGS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |