| Active Ingredient | PRAZOSIN |
| Therapeutic Class | ALPHA ADRENERGIC BLOCKING AGENTS |
| Indications | Benign Prostatic Hypertrophy . |
| Caution |
To reduce incidence of syncope on first dose patient should be given 1mg at bedtime for firstfew doses. Dry mouth, drowsiness and nasal congestion. Dizziness, headache, lack of energy, weakness, palpi More ... |
| Dose Range | Initially 500mcg twice daily for 3-7 days, subsequently adjusting accordingly to response. Maximum dose 2 mg twice daily. |
| Drug Interactions | |
| Pregnancy | Manufacturer advises use only when potential benefit outweighs risk. |
| Breast Feeding | Use prazosin with caution in lactating women as it is distributed in breastmilk. |
| Active Ingredient | TERAZOSIN |
| Therapeutic Class | ALPHA ADRENERGIC BLOCKING AGENTS |
| Indications | Benign prostatic hyperplasia. |
| Caution | Dizziness, lethargy, edema, headache and fatigue.THE FIRST DOSE MUST BE TAKEN AT BEDTIME. Patient should be warned to lie down if symptoms such as dizziness, fatigue or sweating develop, and to rem More ... |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | Manufacturer advises use only when potential benefit outweighs risk. |
| Breast Feeding |
| Active Ingredient | AMLODIPINE | BISOPROLOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | BISOPROLOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | Angina pectoris, Congestive heart failure, Hypertension. |
| Caution |
Hypoglycemia, rash, acne, skin irritation, pruritus, diaphoresis, nausea, vomiting, constipation. |
| Dose Range |
Hypertension and angina: 5-20mg once daily . CHF: Initially .25mg once daily to 10mg daily . A 7.5MG DOSE CAN BE OBTAINED FROM THE 2.5 AND 5MG TABLETS . |
| Drug Interactions | |
| Pregnancy | Bisoprolol has pharmacological effects that may cause harmful effects on pregnan More ... |
| Breast Feeding | Breastfeeding is not recommended during administration of bisoprolol. |
| Active Ingredient | BISOPROLOL | AMLODIPINE |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CARVEDILOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | Angina, Congestive heart failure, impaired left ventricular function after myocardial infarction. |
| Caution | Angina, oedema, hypertension, hypotension, palpitations. |
| Dose Range |
Angina: 12.5mg twice daily increased after 2 days to 25mg once daily. CHF: 3.125mg twice daily increased at two weeks intervals to a maximum of 25mg twice daily for patients with severe heart failure or less than 85kg and 50mg twice daily for those with m |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | LABETALOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | Hypertension. |
| Caution |
Avoid in patients with history of bronchial asthma or chronic obstructive pulmonary disease, conditions associated with severe and prolonged hypotension. Adverse effects include bronchospasm, heada More ... |
| Dose Range | Adult: Hypertension: Initially 100mg twice daily with food gradually increased if necessary to 200-400mg twice daily. Paediatric:1 month-12 years: 1-2 mg/kg three or four times daily.12 to 18 years: initial dose; 50 to 100 mg twice daily with food gradu |
| Drug Interactions | |
| Pregnancy | Labetalol is considered an appropriate agent for the treatment of hypertension i More ... |
| Breast Feeding | Labetalol is distributed in breastmilk. Use with caution in lactating women. |
| Active Ingredient | METOPROLOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | Angina pectoris, cardiac arrhymias, myocardial infarction. |
| Caution | Severe hypotension, bradycardia, congestive heart failure, palpitations, headache, insomnia, tiredness, dizziness, and depression. See propranolol hydrochloride. C.f. prescribing in liver and renal di More ... |
| Dose Range |
Emergency treatment of cardiac arrhythmias: i.v. initial dose of up to 5 mg, at a rate of 1 to 2 mg/minute; repeated, if necessary, at intervals of 5 minutes to a total dose of 10 to 15 mg. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Metoprolol is distributed in breast milk. Use with caution in lactating women. |
| Active Ingredient | PROPRANOLOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications | Hypertension, angina pectoris, cardiac arrthymias,myocardial infarction. Prophylaxis of migraine headaches. |
| Caution | Dose to beta blockade:- bronchoconstriction, cardiac failure, reduced capacity for vigorous exercise, hypoglycemia, decreased peripheral blood flow. Not due to beta blockade:- fatigue, depression, s More ... |
| Dose Range | Adult: Hypertension: 40-80mg twice daily ;usual range:160-320mg daily. Angina: 40mg 2-3 times daily ;maintenance 120-240mg daily. Arrhythmias: 10-40mg 3-4 times daily. Migraine: 80-240mg daily in divided doses.Emergency treatment of cardiac arrhythmias |
| Drug Interactions | |
| Pregnancy | Use with caution during pregnancy. |
| Breast Feeding | Propranolol is distributed in breastmilk. Use with caution. |
| Active Ingredient | SOTALOL |
| Therapeutic Class | BETA ADRENERGIC BLOCKING AGENTS |
| Indications |
Used in acute and prophylactic management of life threatening ventricular tachyarrhythmias as an alternative to amiodarone. |
| Caution | New or worsening of ventricular arrhythmias, fatigue, bradycardia, dizziness. C.f. prescribing in renal disease p. 36. |
| Dose Range |
Arrhythmia: 80mg twice daily initially increasing by 40-80mg every 2-3 days to a maximum of 160-320mg. |
| Drug Interactions | |
| Pregnancy | Sotalol crosses the placenta and should be used during pregnancy only if the pot More ... |
| Breast Feeding | Sotalol is distributed in breastmilk. Use with caution in lactating women. |
| Active Ingredient | CALCIUM CHANNEL BLOCKING AGENTS |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | AMLODIPINE |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | Hypertension, chronic stable angina, vasospastic angina. |
| Caution |
Headache, peripheraledema, dizziness, flushing, tender or bleeding gums, rash. Avoid grapefruit juice. |
| Dose Range | 2.5mg-10mg daily. Dose reductions may be indicated in the elderly or those with hepatic failure, but not necessary in renal impairment. |
| Drug Interactions | |
| Pregnancy | Use in pregnancy only when clearly needed and when the benefits outweigh the pot More ... |
| Breast Feeding |
| Active Ingredient | NIFEDIPINE |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | Angina pectoris when a vasospastic element is present, hypertension. Raynaud's disease. |
| Caution | Avoid the use of diuretics. Headache, flushing, dizziness. Avoid grapefruit juice. Concurrent use may cause severe muscle tenderness and pain..c.f. prescribing in liver and renal p. 15; 33. |
| Dose Range | 20mg twice daily increased if necessary to 40mg twice daily . |
| Drug Interactions | |
| Pregnancy | Nifedipine may inhibit labour. Use during pregnancy only when the potential bene More ... |
| Breast Feeding | Nifedipine is distributed in breastmilk. Use with caution in lactating. |
| Active Ingredient | NIMODIPINE |
| Therapeutic Class | DIHYDROPYRIDINES |
| Indications | Subarachnoid hemorrhage. |
| Caution | Weight loss, cardiac arrythmias, headache, depression, tinnitus. |
| Dose Range | 60mg every four hours started within 4 days for twenty -one days. |
| Drug Interactions | |
| Pregnancy | Nimodipine should be used during pregnancy only when the potential benefits just More ... |
| Breast Feeding | Nimodipine is distributed in breastmilk. Use with caution in lactating women. |
| Active Ingredient | DILTIAZEM |
| Therapeutic Class | CCBs, MISCELLANEOUS |
| Indications | Class IV antiarrhythmic. |
| Caution | Headache, ankle oedema, hypotension, dizziness, bradycardia, AV block. Avoid grapefruit juice. C.f. Prescribing in liver and renal disease p. 13; 28. |
| Dose Range |
Angina: 60-120mg three times daily to a maximum of 360mg daily . Slow release preparation:120-480mg daily . |
| Drug Interactions | |
| Pregnancy | Diltiazem should be used during pregnancy only when the possible benefits outwei More ... |
| Breast Feeding | Diltiazem is distributed in breastmilk and is not recommended for lactating wome More ... |
| Active Ingredient | VERAPAMIL |
| Therapeutic Class | CCBs, MISCELLANEOUS |
| Indications | Class IV antiarrhythmic. |
| Caution | Do not combine with beta blockers. Nausea, vomiting, hypotension. Avoid grapefruit juice. Concurrent use with caffeine may result in enhanced CNS stimulation. C.f. prescribing in liver disease p. 18. |
| Dose Range |
Arrhythmias: 120-480mg 3-4 divided doses. Inj. 5-10mg slow i.v. over 2-3 minutes (preferably with ECG monitoring); Angina: 120mg 3 times daily or sustained release as 120-240mg once daily . |
| Drug Interactions | |
| Pregnancy | Verapamil crosses the placenta and can potentially cause fetal harm. Use during More ... |
| Breast Feeding | Verapamil is distributed in breastmilk. Use is not recommended for lactating wom More ... |