Displaying 1 - 11 of 11
| Active Ingredient | ACE INHIBITORS |
| Therapeutic Class | ACE INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CAPTOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Essential hypertension, congestive heart failure, diabetic nephropathy in patients with type 1 diabetes mellitus with retinopathy . |
| Caution | See notes on page 215. Dry cough, loss of taste, dry mouth, hypotension, drug fever, and rash. C.f. prescribing in renal disease p. 24. |
| Dose Range |
Hypertension: Initially 12.5mg twice daily to a maintenance dose of 25-50mg twice daily . Max. of 50mg 3 times daily is rarely needed. Diabetic nephropathy: Usual dose 25mg 3 times daily . CHF: 6.25- 12.5mg 2-3 times daily.See BDS supply protocols pg. |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Captopril is distributed into breastmilk and is not recommended in lactating wom More ... |
| Active Ingredient | ENALAPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Congestive heart failure, essential hypertension. |
| Caution | Headaches, dizziness and fatigue. See notes on page 215. c.f. prescribing in renal disease p. 28. |
| Dose Range | Hypertension: Initial dose 5mg preferably at bedtime when used alone or 2.5mg with a diuretic. Maintenance dose: 10-20mg daily.Maximum 40mg daily. Congestive Heart Failure: Initial dose 2.5mg daily, usual maintenance dose 20mg as a single or 2 divided d |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Enalapril is distributed in breastmilk and is not recommended in lactating women More ... |
| Active Ingredient | INDAPAMIDE | PERINDOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications |
Mild to moderate hypertension. Edema from congestive heart failure. Not to be used for diuresis. |
| Caution | It may take 2-3 months before optimal blood pressure levels are reached on one tablet daily . An increase in the dosage does not cause any greater reduction in blood pressure. Do not use More ... |
| Dose Range | Adult: One tablet daily before breakfast. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | LISINOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Hypertension. Congestive heart failure. Myocardial Infarction. |
| Caution | See notes on page 215. headache and dizziness.c.f. prescribing in renal disease p. 31. |
| Dose Range |
Hypertension: Initial dose 10mg daily ,if used in addition to diuretic or in cardiac decomp ensation or in volume depletion, initially 2.5-5 mg once daily; Maintenance dose: 20mg once daily. CHF: 2.5mg daily to 5 - 40mg daily. After myocardial infarc |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Lisinopril is excreted in breastmilk and is not recommended in lactating women. |
| Active Ingredient | PERINDOPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | RAMIPRIL |
| Therapeutic Class | ACE INHIBITORS |
| Indications | Mild to moderate hypertension, congestive heart failure. |
| Caution | Nausea, cough, asthenia, abdominal cramps, headache, dizziness. C.f. prescribing in renal disease p. 36. |
| Dose Range | Hypertension: 2.5-10mg once daily. CHF: Initial dose 1.25mg once daily increased to 10 mg daily in 1 or 2 divided doses. After myocardial infarction: Initial dose 2.5 mg twice daily ,increased after two days to 5 mg twice daily. Renal impairment: Initial |
| Drug Interactions | |
| Pregnancy | ACE Inhibitors can cause injury and death to the developing fetus when used in t More ... |
| Breast Feeding | Use ramipril with caution in lactating women. |
| Active Ingredient | LOSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | Hypertension and heart failure, particularly in patients who develop cough with ACE inhibitors. |
| Caution |
Headache, upper respiratory infection, dizziness and cough. Cough, dizziness, edema and nausea, vomiting were significantly more frequent in patients aged 76 years and over. |
| Dose Range | Adult: 25-100mg orally once or twice daily is effective as either monotherapy or in combination with other antihypertensives (diuretics in p articular) in mild to moderate hypertension. See BDS supply protocols pg. 7. |
| Drug Interactions | |
| Pregnancy | Drugs that act on the angiotensin system can cause injury and death to the devel More ... |
| Breast Feeding | Avoid breastfeeding during use of losartan. |
| Active Ingredient | SACUBITRIL | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | Sacubitril and valsartan in fixed combination is used to reduce the risk of cardiovascular death and hospitalization for patients with chronic heart failure (New York Heart Association [NYHA] class 11 More ... |
| Caution | A history of angioedema with an ACE inhibitor or angiotensin 11receptor antagonist. Concomitant use with ACE inhibitors. Sacubitril/valsartan should not be administered within 36 hours of switching f More ... |
| Dose Range | Adult: The recommended initial dose of sacubitril /valsartan in patients with CHF who are stabilised on an ACE or ARB is sacubitril 49mg /valsartan 51 mg twice daily. 36 hours should have relapsed before starting sacubitril/valsartan, if patient was on a |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | TELMISARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications |
Hypertension, left ventricular dysfunction after my ocardial infarction, heart failure when ACE inhibitors are not tolerated. |
| Caution | Headache, dizziness, viral infection, upper respiratory tract infection, cough, diarrhea, drowsiness, rhinitis, sinusitis, backache, stomach ache, nausea, pharyngitis and joint pain. The drug is contr More ... |
| Dose Range | Hypertension: Initial dose 80mg once daily, with or without food. The dose may be increased to 160mg daily if initial response is insufficient. Maximum dose 320mg once daily. CHF: Initially 40mg twice daily increased as tolerated to 160mg twice. M |
| Drug Interactions | |
| Pregnancy | Drugs that act on the angiotensin system can cause injury and death to the devel More ... |
| Breast Feeding | Avoid breastfeeding while using losartan. |