| Active Ingredient | DIURETICS |
| Therapeutic Class | DIURETICS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | FRUSEMIDE |
| Therapeutic Class | LOOP DIURETICS |
| Indications | Resistant oedema, renal failure, pulmonary oedema. |
| Caution | Fluid or electrolyte disturbances hyponatremia, hypotension, gout and glucose intolerance; deafness in renal failure; may precipitate prostatic urinary retention; toxicity with cephaloridine.c.f. pres More ... |
| Dose Range | Adults and Children over 12 years: 20-80mg up to a max. of 600mg in severe cases. May be more effective given twice daily . Slow i.v. 20-50mg. Pediatric 1 month-12 years: 0.5mg-2mg/kg, 2-3 times daily (500mg tablet available as a Category B at Q.E.H. Pharmacy for use by Consultant in renal dialysis unit only). |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | MANNITOL |
| Therapeutic Class | OSMOTIC DIURETICS |
| Indications | Forced diuresis, cerebral oedema. |
| Caution | Pulmonary odema, cardiac failure. May cause chills, fever. |
| Dose Range | 50-200g in infusion as 10% or 20% solution; over 24 hours, according to circumstances. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | BENDROFLUAZIDE |
| Therapeutic Class | THIAZIDE DIURETICS |
| Indications |
Mild cardiac failure and fluid retention, mild hypotensive and to potentiate other drugs in severe hypertension. For use only in patients who are hypocalcemic. |
| Caution | Fluid and electrolyte disturbances. [Hypokalemia, hyperuricaemia, hy p ergly caemia]. Diuretic-induced hypokalaemia may enhance the toxicity of digoxin unless adequate potassium supplementation is More ... |
| Dose Range |
Adult: Hypertension: 2.5mg daily . Paediatric: 50-100mcg/kg per day . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CHLORTHALIDONE |
| Therapeutic Class | THIAZIDE LIKE DIURETICS |
| Indications | Thiazides are used in the management of edema associated with heart failure, or a history of fluid retention, mild hypertension and to potentiate other hypertensive drugs in severe hypertension. |
| Caution | Alkalosis hypochloraemic; constipation; diarrhoea; dizziness; dry mouth; electrolyte imbalance; erectile dysfunction; fatigue; headache; hyperglycaemia; hyperuricaemia; nausea; postural hypotension; s More ... |
| Dose Range |
Oedema- Adult Initially 5–10 mg once daily or on alternate days, dose to be taken in the morning, then maintenance 5–10 mg 1–3 times a week. Hypertension - 2.5 mg daily, dose to be taken in the morning, higher doses are rarely necessary. |
| Drug Interactions | |
| Pregnancy | Thiazides and related diuretics should not be used to treat gestational hyperten More ... |
| Breast Feeding |
The amount present in milk is too small to be harmful. Large doses may suppress More ... |
| Active Ingredient | INDAPAMIDE |
| Therapeutic Class | THIAZIDE LIKE DIURETICS |
| Indications |
Mild to moderate hypertension. Edema from congestive heart failure. Not to be used for diuresis. |
| Caution | It may take 2-3 months before optimal blood pressure levels are reached on one tablet daily . An increase in the dosage does not cause any greater reduction in blood pressure. Do not use More ... |
| Dose Range | Adult: One tablet daily before breakfast. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |