Rx Name [SPIRONOLACTONE, 243220]
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ALDACTONE 100MG TAB (PFI/STO) SPIRONOLACTONE
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243220
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ALDOSTERONE RECEPTOR ANTAGONIST
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Oedema in Congestive Heart Failure (CHF).It is frequently given with the thiazides, furosemide, or similar diuretics, where it adds to their natriuretic but diminishes their kaliuretic effects, hence conserving potassium in those at risk from hypokala
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May cause hyperkalemia in renal failure; gynaecomastia, nausea,
vomiting, drowiness. C.f. prescribing in renal disease p. 36. |
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Adults and Children over 12yrs: Odema: 100-200mg daily in single or divided doses to a maximum of 400mg daily. Moderate to severe heart failure (Adjunct): initially 25mg increased to a maximum of
50mg once daily . Pediatric 1mth-12yrs: 1-3mg/kg in 1 or 2 |
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Safe use of spironolactone during pregnancy has not been established. The drug should be used during pregnancy only when the potential benefits outweigh the possible risks to the fetus.
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Spironolactone enters breastmilk and is not recommended in lactating women.
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