Rx Name [PYRIDOSTIGMINE, 1204]
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MESTINON 60MG TAB (VCL/COL) PYRIDOSTIGMINE
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1204
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PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS
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Myasthenia gravis. Preferable to neostigmine because of longer half-life (1-3 hours). Delayed format is available.
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As for neostigmine; note "Cholinergic Crises' or paralysis due to over medication (abdominal cramp s most useful warning). C.f. prescribing in renal disease p. 36.
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Adult: 60-180mg every 3-6 hours, carefully titrated for optimal effects. Paediatric: under 6 y ears: 30 mg; 6 to 12 y ears: 60 mg, increasing to a maximum of 30 to 360 mg daily .
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Breastfeeding is not recommended during treatment with pyridostigmine.
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