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| Active Ingredient | PYRIDOSTIGMINE |
| Therapeutic Class | PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS |
| Indications | Myasthenia gravis. Preferable to neostigmine because of longer half-life (1-3 hours). Delayed format is available. |
| Caution | As for neostigmine; note "Cholinergic Crises' or paralysis due to over medication (abdominal cramp s most useful warning). C.f. prescribing in renal disease p. 36. |
| Dose Range | Adult: 60-180mg every 3-6 hours, carefully titrated for optimal effects. Paediatric: under 6 y ears: 30 mg; 6 to 12 y ears: 60 mg, increasing to a maximum of 30 to 360 mg daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Breastfeeding is not recommended during treatment with pyridostigmine. |