Rx Name [BOSENTAN, 4848]
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PMS-BOSENTAN 125MG TAB (PMS/COL)
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4848
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VASODILATING AGENTS MISCELLANEOUS
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Pulmonary Hypertension.
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Contra-indicated in patients with moderate to severe hepatic impairment, headache, nasopharyngitis, flushing, oedema, hypotension, dizziness, palpitations, gastrointestinal disturbances, pruritus, rash, fatigue, muscle cramps, and anaemia. The dosage of the drug should be reduced gradually if being discontinued.
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12 years and older: Initially 62.5 mg twice daily, increased after 4 weeks to a maintenance dose of 125 mg twice daily. Patients with low body weight (below 40kg) 62.5 mg twice daily.
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