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Active Ingredient BOSENTAN
Therapeutic Class VASODILATING AGENTS MISCELLANEOUS
Indications Pulmonary Hypertension.
Caution Contra-indicated in patients with moderate to severe hepatic impairment, headache, nasopharyngitis, flushing, oedema, hypotension, dizziness, palpitations, gastrointestinal disturbances, pruritus More ...
Dose Range 12 years and older: Initially 62.5 mg twice daily, increased after 4 weeks to a maintenance dose of 125 mg twice daily. Patients with low body weight (below 40kg) 62.5 mg twice daily.
Drug Interactions
Pregnancy
Breast Feeding