| Active Ingredient | BETHANECHOL |
| Therapeutic Class | PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS |
| Indications | Urinary retention, post-operative dystension due to paralyticileus. |
| Caution | Take on empty stomach. May cause dizziness or drowsiness. See neostigmine. |
| Dose Range | Adult: 10-50mg 3-4 times daily . Inj. 5mg s.c. and repeat (double if necessary , according to individual response). |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | DONEPEZIL |
| Therapeutic Class | PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS |
| Indications | Mild to moderate dementia in Alzheimer’s disease. |
| Caution | Nausea, diarrhea, fatigue, headache, dizziness, agitation, muscle cramps. |
| Dose Range |
Initially 5mg once daily at bedtime increased if necessary after 4-6 weeks to 10mg once daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | NEOSTIGMINE |
| Therapeutic Class | PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS |
| Indications | Treatment of myasthenia gravis but very short acting. (Half-life may be less than 1 hour). |
| Caution |
Prototype anticholinesterase, para-sympathomimetic. Nausea, vomiting, abdominal cramps, salivation, diarrhoea, sweating, miosis, brady cardia, hypotension, agitation and dreaming. Weakness with ove More ... |
| Dose Range | Adult: 15-60mg every 2-4 hours as necessary . 1-2.5mg i.m. in emergencies. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PYRIDOSTIGMINE |
| Therapeutic Class | PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS |
| Indications | Myasthenia gravis. Preferable to neostigmine because of longer half-life (1-3 hours). Delayed format is available. |
| Caution | As for neostigmine; note "Cholinergic Crises' or paralysis due to over medication (abdominal cramp s most useful warning). C.f. prescribing in renal disease p. 36. |
| Dose Range | Adult: 60-180mg every 3-6 hours, carefully titrated for optimal effects. Paediatric: under 6 y ears: 30 mg; 6 to 12 y ears: 60 mg, increasing to a maximum of 30 to 360 mg daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Breastfeeding is not recommended during treatment with pyridostigmine. |
| Active Ingredient | RIVASTIGMINE |
| Therapeutic Class | PARASYMPATHOMIMETIC (CHOLINERGIC) AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |