Displaying 1 - 7 of 7
Active Ingredient SOMATROPIN
Therapeutic Class SOMATROPHIN AGONIST
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient HYDROXYPROGESTERONE
Therapeutic Class PROGESTINS
Indications Amenorrhea, pre-term labour (prophylaxis).
Caution Changes in appetite or weight, fluid retention, oedema, acne, chloasma (melasma), allergic skin rashes.
Dose Range Pre-term labour (prophylaxis): 250-500mg intramuscularly weekly during first half of pregnancy or longer. Amenorrhea:
375mg intramuscularly .
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient MEDROXYPROGESTERONE
Therapeutic Class PROGESTINS
Indications Anovulatory dysfunctional uterin e bleeding (DUB), post
menopausal hormone replacement therapy, contraception, carcinoma of the endometrium.
Caution Fluid retention, menstrual disorders. Use with caution in conditions which worsen fluid retention. c.f. prescribing in liver disease p. 15.
Dose Range Oral: 2.5-10mg daily for at least 10 day s p er month as HRT; daily
from day s 16 or 21 of cycle for 5-10 days in anovulatory DUB. Higher p arenteral doses are required in endometrical cancer.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient NORETHISTERONE
Therapeutic Class PROGESTINS
Indications See Medroxy progesterone Acetate.
Caution c.f. prescribing in liver disease p. 15. Contraindicated in pregnancy . Ten times more potent than medroxy progesterone.
Dose Range Dysfunctional Uterine Bleeding: 1-2 tab. Daily for 6-12 days. To
prevent relapse, 1-2 tab daily from 16th-25th day of cycle, combined
with oestrogen if necessary . Endometriosis: 1 tab. Daily from 5th-
25th day of cycle for 6 mth or ½ tab. Daily , continu
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient THYROXINE
Therapeutic Class THYROID AGENTS
Indications Hypothyroidism.
Caution Angina, sweating, headache, diarrhoea, tachycardia (features of thyrotoxicosis), weight loss, restlessness.
Dose Range 50-100mcgs daily increased by 25-50mcg at intervals of about 4
weeks. Maintenance Dose: 100-200mcgs daily. Best taken on an empty stomach Start at low dose (12.5-50mcg daily ) in elderly or patients with ischaemic heart disease.
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient CARBIMAZOLE
Therapeutic Class ANTI-THYROID AGENTS
Indications Hyperthyroidism.
Caution Monitor carefully in pregnancy and breast feeding as overdose may cause fetal and neonatal thyroid depression. May cause skin rashes, joint swelling, arthalgias.
Dose Range Adult: 15- 40 mg (up to 60 mg) daily in divided doses until patient is euthyroid. Maintenance dose 5 to 15 mg daily , as a single dose. Pediatric: 0.75 mg/kg (max.30 mg) daily as single or divided doses.
12-18 y rs: 30mg daily initially , in single or div
Drug Interactions
Pregnancy
Breast Feeding
Active Ingredient PROPYLTHIOURACIL
Therapeutic Class ANTI-THYROID AGENTS
Indications Hyperthyroidism.
Caution Fever, leukopenia, rash.
Dose Range Adult: 200-400 mg daily (600-1200 mg in severe cases) in single or divided doses until euthyroid. Maintenance dose: 50-150 mg daily .
Paediatric: neonates: 2.5-5 mg/kg twice daily ; 1 month to 1 yr:
2.5 mg/kg 3 times daily : 1-
18y rs: 25 -100mg 3 tim
Drug Interactions
Pregnancy
Breast Feeding