| Active Ingredient | CITALOPRAM |
| Therapeutic Class | SELECTIVE SEROTONIN REUPTAKE INHIBITORS |
| Indications | Major depression, obsessive-compulsive disorder, panic disorder. |
| Caution | As for fluoxetine. |
| Dose Range | Initial dose of 20mg/day as a single dose, increase as required after one week to a maximum of 40mg/day . |
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| Pregnancy | |
| Breast Feeding |
| Active Ingredient | DESVENLAFAXINE |
| Therapeutic Class | SELECTIVE SEROTONIN REUPTAKE INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ESCITALOPRAM |
| Therapeutic Class | SELECTIVE SEROTONIN REUPTAKE INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
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| Pregnancy | |
| Breast Feeding |
| Active Ingredient | FLUOXETINE |
| Therapeutic Class | SELECTIVE SEROTONIN REUPTAKE INHIBITORS |
| Indications | Depression, obsessive compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder. |
| Caution | The main side effect is nausea; other side effects are hypotension, CNS symptoms (headache, anxiety, nervousness, insomnia), dry mouth, anorexia and visual disturbances; weight loss (but not weight ga More ... |
| Dose Range | Usual effective dose for depression, obsessive compulsive disorder and premenstrual dysphoric disorder is 20mg/day in the morning; however, doses up to 80mg/day have been used. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PAROXETINE |
| Therapeutic Class | SELECTIVE SEROTONIN REUPTAKE INHIBITORS |
| Indications | Major depression, obsessive-compulsive disorder, panic disorder. |
| Caution | As for fluoxetine. |
| Dose Range | Adult: 10-60mg daily. Maximum dose in the elderly 40mg daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SERTRALINE |
| Therapeutic Class | SELECTIVE SEROTONIN REUPTAKE INHIBITORS |
| Indications |
Major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, premenstrual dysphoric disorder and social phobia. |
| Caution | Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorde More ... |
| Dose Range |
Adult: 50 mg daily increased, if necessary, in increments of 50 mg at intervals of at least a week to a maximum of 200 mg daily. Child: Obsessive-compulsive disorder: children 6-12 yr, 25mg/day, 13-17 yr, 50mg/day orally as a single dose in the morning or |
| Drug Interactions | |
| Pregnancy | Category C |
| Breast Feeding |
| Active Ingredient | AMITRIPTYLINE |
| Therapeutic Class | TRICYCLICS & OTHER NOREPINEPHRINE REUPTAKE INHIBIT |
| Indications | Agitated depression. |
| Caution | Acute retention especially in prostatic hypertrophy. Tricyclics may antagonise the action of adrenergic neurone blocking drugs e.g. guanethidine, and may seriously impair their antihypertensive effec More ... |
| Dose Range | 50-200mg daily in divided doses. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CLOMIPRAMINE |
| Therapeutic Class | TRICYCLICS & OTHER NOREPINEPHRINE REUPTAKE INHIBIT |
| Indications | Most useful in obsessional and phobic disorders. |
| Caution | See amitriptyline hydrochloride. Weight gain, urinary retention, tremor. C.f. prescribing in liver disease. P. 12. |
| Dose Range |
Initially 25 mg daily (or 10 mg daily for elderly patients or those sensitive to tricyclics) increased gradually over two weeks to 100 to 150 mg daily . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | IMIPRAMINE |
| Therapeutic Class | TRICYCLICS & OTHER NOREPINEPHRINE REUPTAKE INHIBIT |
| Indications | Treatmment of juvenile enuresis. Depressive illness. |
| Caution | Causes less confusion in the elderly. c.f. prescribing in liver disease p.14. See amitripty line. |
| Dose Range |
Adult: Initially up to 75mg in divided doses, gradually increasing to 150-200mg. In the elderly initial dose of 10mg daily increased gradullay to 30-50mg daily. Paediatric: 6-7 yrs 25 mg 8-11 yrs 25- 50mg, 11-18yrs 50-75mg at bedtime innocturnal enuresis |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |