| Active Ingredient | DILTIAZEM |
| Therapeutic Class | CCBs, MISCELLANEOUS |
| Indications | Class IV antiarrhythmic. |
| Caution | Headache, ankle oedema, hypotension, dizziness, bradycardia, AV block. Avoid grapefruit juice. C.f. Prescribing in liver and renal disease p. 13; 28. |
| Dose Range |
Angina: 60-120mg three times daily to a maximum of 360mg daily . Slow release preparation:120-480mg daily . |
| Drug Interactions | |
| Pregnancy | Diltiazem should be used during pregnancy only when the possible benefits outwei More ... |
| Breast Feeding | Diltiazem is distributed in breastmilk and is not recommended for lactating wome More ... |
| Active Ingredient | VERAPAMIL |
| Therapeutic Class | CCBs, MISCELLANEOUS |
| Indications | Class IV antiarrhythmic. |
| Caution | Do not combine with beta blockers. Nausea, vomiting, hypotension. Avoid grapefruit juice. Concurrent use with caffeine may result in enhanced CNS stimulation. C.f. prescribing in liver disease p. 18. |
| Dose Range |
Arrhythmias: 120-480mg 3-4 divided doses. Inj. 5-10mg slow i.v. over 2-3 minutes (preferably with ECG monitoring); Angina: 120mg 3 times daily or sustained release as 120-240mg once daily . |
| Drug Interactions | |
| Pregnancy | Verapamil crosses the placenta and can potentially cause fetal harm. Use during More ... |
| Breast Feeding | Verapamil is distributed in breastmilk. Use is not recommended for lactating wom More ... |