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Active Ingredient DILTIAZEM
Therapeutic Class CCBs, MISCELLANEOUS
Indications Class IV antiarrhythmic.
Caution Headache, ankle oedema, hypotension, dizziness, bradycardia, AV block. Avoid grapefruit juice. C.f. Prescribing in liver and renal disease p. 13; 28.
Dose Range Angina: 60-120mg three times daily to a maximum of 360mg daily .
Slow release preparation:120-480mg daily .
Drug Interactions
Pregnancy Diltiazem should be used during pregnancy only when the possible benefits outwei More ...
Breast Feeding Diltiazem is distributed in breastmilk and is not recommended for lactating wome More ...
Active Ingredient VERAPAMIL
Therapeutic Class CCBs, MISCELLANEOUS
Indications Class IV antiarrhythmic.
Caution Do not combine with beta blockers. Nausea, vomiting, hypotension. Avoid grapefruit juice. Concurrent use with caffeine may result in enhanced CNS stimulation. C.f. prescribing in liver disease p. 18.
Dose Range Arrhythmias: 120-480mg 3-4 divided doses. Inj. 5-10mg slow i.v. over 2-3 minutes (preferably with ECG monitoring); Angina: 120mg
3 times daily or sustained release as 120-240mg once daily .
Drug Interactions
Pregnancy Verapamil crosses the placenta and can potentially cause fetal harm. Use during More ...
Breast Feeding Verapamil is distributed in breastmilk. Use is not recommended for lactating wom More ...