| Active Ingredient | AMLODIPINE | VALSARTAN |
| Therapeutic Class | HYPOTENSIVE AGENTS, MISCELLANEOUS |
| Indications | Hypertension in patients stabilised on the individual components. |
| Caution | As for amlodipine, valsartan. |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SACUBITRIL | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | Sacubitril and valsartan in fixed combination is used to reduce the risk of cardiovascular death and hospitalization for patients with chronic heart failure (New York Heart Association [NYHA] class 11 More ... |
| Caution | A history of angioedema with an ACE inhibitor or angiotensin 11receptor antagonist. Concomitant use with ACE inhibitors. Sacubitril/valsartan should not be administered within 36 hours of switching f More ... |
| Dose Range | Adult: The recommended initial dose of sacubitril /valsartan in patients with CHF who are stabilised on an ACE or ARB is sacubitril 49mg /valsartan 51 mg twice daily. 36 hours should have relapsed before starting sacubitril/valsartan, if patient was on a |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications |
Hypertension, left ventricular dysfunction after my ocardial infarction, heart failure when ACE inhibitors are not tolerated. |
| Caution | Headache, dizziness, viral infection, upper respiratory tract infection, cough, diarrhea, drowsiness, rhinitis, sinusitis, backache, stomach ache, nausea, pharyngitis and joint pain. The drug is contr More ... |
| Dose Range | Hypertension: Initial dose 80mg once daily, with or without food. The dose may be increased to 160mg daily if initial response is insufficient. Maximum dose 320mg once daily. CHF: Initially 40mg twice daily increased as tolerated to 160mg twice. M |
| Drug Interactions | |
| Pregnancy | Drugs that act on the angiotensin system can cause injury and death to the devel More ... |
| Breast Feeding | Avoid breastfeeding while using losartan. |