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Active Ingredient PENICILLAMINE
Therapeutic Class HEAVY METAL ANTAGONISTS
Indications Acute copper (or lead) poisoning, Wilson's disease. Third line drug for rheumatoid arthritis (to reduce cystine levels).
Caution Epigastric pain, nausea, rash c.f. prescribing in renal disease p.
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Dose Range Adult: 1-2g daily in divided doses (In R. A: 125mg-250mg with doses increases over a 3-4 mth period to a maximum of 1.5g). Pediatric: 2.5-10mg/kg twice daily .
Drug Interactions
Pregnancy
Breast Feeding