Formulary Monographs [PENICILLAMINE, 6400]
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PENICILLAMINE
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HEAVY METAL ANTAGONISTS
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Acute copper (or lead) poisoning, Wilson's disease. Third line drug for rheumatoid arthritis (to reduce cystine levels).
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Epigastric pain, nausea, rash c.f. prescribing in renal disease p.
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Adult: 1-2g daily in divided doses (In R. A: 125mg-250mg with doses increases over a 3-4 mth period to a maximum of 1.5g). Pediatric: 2.5-10mg/kg twice daily .
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