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| Active Ingredient | CYCLOPHOSPHAMIDE |
| Therapeutic Class | ANTINEOPLASTICS |
| Indications | Non-Hodgkin’s lymphomas. |
| Caution | High fluid intake will help to prevent haemorrhagic cystitis (3-4 litres/day ). C.f. prescribing in renal disease p. 27. |
| Dose Range | Low-dose: 2-6 mg/kg weekly as a single i.v. dose/ in divided oral doses; moderate-dose:10-15 mg/kg weekly as a single i.v. dose; High-dose: 20-40 mg/kg as a single i.v. dose every 10-20 days, depending on the disease being treated, condi |
| Drug Interactions | |
| Pregnancy | Cyclophosphamide can cause fetal toxicity when administered to pregnant women, b More ... |
| Breast Feeding | Discontinue breast-feeding during and for 36 hours after stopping treatment. |