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| Active Ingredient | CILASTATIN | IMIPENEM |
| Therapeutic Class | CARBAPENEMS |
| Indications |
Aerobic and anaerobic Gram-positive and Gram-negative infections; (not indicated for CNS infections) hospital-acquired septicaemia. |
| Caution |
Diarrhoea; eosinophilia; nausea (may reduce rate of infusion); rash; vomiting |
| Dose Range | Adult: 500mg every 6 hours, alternatively 1g every 8 hours. |
| Drug Interactions | |
| Pregnancy | Manufacturer advises avoid unless potential benefit outweighs risk. Both imipene More ... |
| Breast Feeding | Present in milk but unlikely to be absorbed. |