Rx Name [SULFAMETHOXAZOLE|TRIMETHOPRIM, 081220]

Rx Name	CO-TRIMOXAZOLE 400MG \| 80MG TAB (HEA/RXP) SULFA
Active Ingredient	SULFAMETHOXAZOLE \| TRIMETHOPRIM
Therapeutic Code	081220
Therapeutic Class	SULPHONAMIDES
Indications	Urinary tract infections; typhoid, invasive Salmonellosis; H. influenzae. Infections, exacerbations of chronic bronchitis.
Caution	Discontinue if skin rash develops. Nausea and vomiting may occur. Sensitivity to sunlight increases while taking this medication. Use a sunscreen when outdoors. C.f. prescribing in renal disease p. 27.
Dose Range	Adult: 1-2 tablets every 8-12 hours. Pediatric: 6 weeks - 5 months: ½ teaspoonful every 12 hours. 6 months - 5 years: 1 teaspoonful every 12 hours. 6-12 years: 2 teaspoonsful every 12 hours. Take with a full glass of water and drink several glasses of wat
Drug Interactions
Pregnancy	Co-trimoxazole crosses the placenta and may interfere with folic acid metabolism. Should be used during pregnancy only when the potential benefits justify the possible risks to the fetus.
Breast Feeding	Co-trimoxazole is distributed into milk with small risk of kernicterus in jaundiced infants and of haemolysis in G6PD-deficient infants (due to sulfamethoxazole).
Drug Note