Rx Name [ALTEPLASE, 201220]
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ACTILYSE 50MG INJ (BOE/STO) ALTEPLASE
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201220
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THROMBOLYTIC AGENTS
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Intravenous alteplase is effective in producing recanalization of occluded coronary arteries following acute my ocardial infarction. Also effective in the treatment of acute massive pulmonary embolism and stroke and may have utility in other vascular d
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Bleeding complications, reperfusion arrhythmias and reinfarction are the primary concerns of therapy .
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The recommended dose to produce recanalization following my ocardial infarction is 100mg given as a “front -loaded” infusion.
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Alteplase should be used during pregnancy only when clearly needed. There is a risk of maternal haemorrhage throughout pregnancy and post-partum and also a theoretical risk of fetal haemorrhage throughout pregnancy.
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