Formulary Monographs [SERUMS TOXOIDS AND VACCINES, <a href="drug_notes

Formulary Monographs [SERUMS TOXOIDS AND VACCINES, 8000]

Active Ingredient	SERUMS TOXOIDS AND VACCINES
Therapeutic Code	8000
Therapeutic Class	SERUMS, TOXOIDS AND VACCINES
Indications
Caution
Dose Range
Drug Interactions
Pregnancy
Breast Feeding
Drug Note	Immunisation Schedule 2 months - 1st D.P.T.,Hep . B, Hib,Polio, Pneumococcus 4 months - 2ndD.P.T.,Hep . B, Hib,Polio, Pneumococcus 6 months - 3rdD.P.T.,Hep . B, Hib,Polio, Pneumococcus 12 months - 1stM .M .R.& Chicken Pox 18 months - 1st Booster D.P.T & Polio 3-5 y ears - 2nd M .M .R. 4 ½ y ears - 2nd Booster D.P.T& Polio 5 - 6 y ears - B. C. G (at school) 10 – 11+ y ears - 3rd Booster D.T. & Polio 11+ y ears HPV (at school) DOSAGE DPT - 0.5ml given intra-muscularly . Polio - 0.2ml orally . Measles or M M R - 0.5ml subcutaneously in outer aspect of upper arm. STORAGE OF VACCINE Diphtheria, Tetanus, and Pertussis vaccine should be stored between 2 - 8 degrees C. Should not be frozen. Measles or M M R - Best preserved by storing frozen at a temperature of - 10 degrees C to - 30 degrees C or in refrigerator at temperature between +2 degrees C and +8 degrees C Precautions should be taken to ensure that such temperatures are observed during transportation of vaccine and storage in order to maintain the cold chain. CONTRAINDICATIONS 1. Febrile illness. 2. Diarrhoea. (OPV should be p ostp oned). 3. Convulsion within 1-48 hours following pertussis - omit pertussis at next visit. 4. Rubella should not be given to females when pregnancy is suspected. 5. Children who have leukaemia or who are on immuno- suppresive therapy e.g. antimetabolites, corticosteroids or in cases of primary immunodeficiency states. e.g. hypogammaglobulinemia. ADVERSE REACTIONS Diphtheria, Tetanus, and Pertussis - (i) Mild local reaction consisting of pain, erythema, tenderness and induration at injection site are common and may be associated with systemic reactions including mild to moderate transient fever, chills, malaise and irritability ; (ii) more marked reactions such as fever (over 40 degrees C), drowsiness, convulsions, excessive screaming or transient shock-like episodes may occur. Occurence of these features is a CONTRAINDICATION to further injections. Measles Mild fever, rash may occur 5-12 days after vaccine. Omit Measles if child has known allergy to eggs or chicken.

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