Formulary Monographs [MILRINONE LACTATE, 240408]

MILRINONE LACTATE
CARDIOTONIC AGENTS
Short-term treatment of severe congestive heart failure unresponsive to conventional maintenance therapy; acute heart failure after cardiac surgery .
Monitor renal function. Ectopic beats, ventricular tachycardia, supraventricular arrhythmias, hypotension, headache.
Intravenous injection over 10 minutes, either undiluted or diluted before use, 50 micrograms/kg followed by intravenous infusion at a rate of 375-75 nanograms/kg/minute, usually for up to 12 hours following surgery or for 48-72 hours in congesti
Manufacturer advises use only if potential benefit outweighs risk.
Use milrinone with caution in lactating women.