Formulary Monographs [MELPHALAN, 1000]
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MELPHALAN
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ANTINEOPLASTICS
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Breast cancer, multiple myeloma
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Anorexia, nausea and vomiting, leukopenia, thrombocytopenia and
anaemia. Severe bone marrow suppression with resulting infection or bleeding may occur. |
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Breast Cancer: 150mcg/kg daily in divided doses for 5 days repeated every 6 weeks. Multiple Myeloma: 6mg daily for 2-3 weeks with with rest periods of up to 6 weeks.
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Therapy may suppress ovarian function and result in amenorrhea
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Not recommended during therapy.
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