Formulary Monographs [LOPINAVIR|RITONAVIR, 08180892]
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LOPINAVIR | RITONAVIR
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ANTIRETROVIRALS MISCELLANEOUS
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In combination with other antiretrovirals for the treatment of HIV-
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Headache, fatigue, diarrhoea and nausea. Increased blood lipids and infrequent cases of pancreatitis have been reported. As with other protease inhibitors, Lipodystrophy syndrome (i.e., increased blood glucose, redistribution of body fat) is possible. Store solution at room temperature but refrigerate capsules.
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Adults and Pediatric12 years and older: Lopinavir 400/100 millgrams (mg) (lopinavir/ritonavir, respectively) twice daily taken with food. A dose increase to 533/133 mg twice daily is recommended whe lopinavir/ritonavir is taken concomitantly with
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Avoid oral solution due to high alcohol and propylene glycol content; use tablets only if potential benefit outweighs risk
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The Centers for Disease Control and Prevention (CDC) and other experts recommend that HIV-infected women not breast-feed infants, regardless of antiretroviral therapy due to the risk of transmitting the virus through breastfeeding.
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