Formulary Monographs [IOVERSOL, 3668]
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IOVERSOL
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ROENTGENOGRAPHY
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Ioversol is an iodinated radiographic contrast medium that is given intra-arterially or intravenously for angiography and urography. For other procedures, it can be injected into body cavity or injected into gall bladder, bilary ducts or spleen.
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Most reactions occur within 5 to 10 minutes and are mild and transient; however, severe, life-threatening reactions may also occur, and delayed reactions have been reported. Common side effect is flushing or a sensation of heat, which causes vasodilation in response to the osmolarity of the solution. Urticaria, pruritus, pallor, sweating,a metallic taste, weakness, coughing, rhinitis, sneezing, lachrymator, and visual disturbances may also occur.
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Ioversol injection 64% (marketed as Optiray 300) - bolus injection: 25 to 75 mL, infusion: 50 to 150 mL Ioversol injection 68% (marketed as Optiray 320) - bolus injection: 25 to 75 mL, infusion: 50 to 150 mL Ioversol injection 74% (marketed as Optiray 350
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