Formulary Monographs [HYDRALLAZINE, 240820]
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HYDRALLAZINE
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DIRECT VASODILATOR
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Moderate to severe hypertension. As a vasodilator decreasing
afterload in intractable heart failure. To be used with a diuretic and beta blocker. |
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May cause angina in predisposed patients. Reversible SLE type syndrome with prolonged use of more than 200mg/day. Must be used with caution in patients on MAOI's or tricyclics. Severe headache, palpitations, vomiting, nausea, tachycardia and diarrhoea. C.f. prescribing in renal disease p. 30.
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Oral: 50-100mg daily in 2 divided doses. Inj: 5-10mg i.m. or i.v. by
slow titration over 20-30 minutes or 200-300mcg/min by slow iv infusion. |
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Manufacturer advises that hydralazine should not be used before third trimester during pregnancy.
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Use with caution as hydralazine is distributed into breastmilk but is not known to be harmful.
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