Formulary Monographs [EPIRUBICIN, 1000]
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EPIRUBICIN
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ANTINEOPLASTICS
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Acute leukaemias, lymphomas, solid tumours.
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Leukopenia, nausea and vomiting, diarrhoea, thrombocytopenia, EKG changes, congestive cardiac failure secondary to a diffuse cardiomyopathy, alopecia. C.f. prescribing in liver disease p. 13.
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Avoid during pregnancy. Teratogenic effects and embryotoxicity were noted in animal studies.
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It is unknown whether epirubicin is distributed in milk. Breastfeeding is therefore not recommended due to the potential risks of adverse effects in the nursing infant.
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