Formulary Monographs [DAPAGLIFLOZIN, 682018]

DAPAGLIFLOZIN
SODIUM-GLUCOSE COTRANSPORTER INHIBITOR
As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
Back pain; balanoposthitis; dizziness; dyslipidaemia; hypoglycaemia (in combination with insulin or sulphonylurea); increased risk of genital mycotic infection in both males and females; rash; increase risk of urinary disorders.
The usual oral dose is 5 or 10 mg once daily. Doses of insulin, sulfonylurea, and other insulin secretagogues may need to be lowered when used with dapagliflozin. The dose of dapagliflozin should be reduced in hepatic impairment.