Formulary Monographs [CLINDAMYCIN HYDROCHLORIDE, 08122820]
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CLINDAMYCIN HYDROCHLORIDE
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LINCOMYCINS
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Staphylococcal bone or joint sepsis, peritonitis (alternative to gentamicin and metronidazole). Effective againstmany anaerobes. Bacteroides fragilis. Gram-positive cocci including penicillin-resistant staphylococci.
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Diarrhoea pseudomembranous colitis. This is the commonest antibiotic causing it (responds to oral metronidazole or vancomycin). Report any excess diarrhoea, do not take anti-diarrhoeal drugs. C.f. prescribing in liver disease p. 12.
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Adult: 150-450mg every 6 hours. Pediatricunder 12 years: 3-6 mg/kg/day every 6 hours. See BDS supply protocols pg. 3.
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Not known to be harmful.
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Clindamycin has the potential to cause adverse effects on the breastfed infant's gastrointestinal flora. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea or blood in the stool.
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