Formulary Monographs [CARBOPLATIN, 1000]
|
|
CARBOPLATIN
|
|
|
|
|
|
ANTINEOPLASTICS
|
|
|
Advanced ovarian cancers and of small-cell lung cancer.
|
|
|
As for cisplatin. Myelosuppression may be more severe than cisplatin and prolonged in patients with impaired renal function.
|
|
|
Adult: dose of carboplatin is determined according to renal function rather than body surface area.
|
|
|
|
|
|
Carboplatin can cause fetal toxicity when administered to pregnant women, but potential benefits from use of the drug may be acceptable in certain conditions despite possible risks to the fetus.
|
|
|
Because of the potential for serious adverse reactions to carboplatin in nursing infants if the drug were distributed into milk, nursing should be discontinued during carboplatin therapy.
|
|
|
|