Formulary Monographs [AZATHIOPRINE, 1000]
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AZATHIOPRINE
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ANTINEOPLASTICS
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Usually as an adjunct to corticosteroids, in autoimmune disorders, e.g. SLE and rheumatoid arthritis. C.f. prescribing in liver and renal disease p. 11; 23.
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leukopenia, infection,abdominal pain, alopecia, diarrhea, fever, rash, bone marrow suppression, myalgia
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1-3mg/kg daily , usually 100-200mg daily . Take with food.
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Azathioprine can cause fetal harm when administered to a pregnant woman.The manufacturer also states that azathioprine should not be used for the treatment of rheumatoid arthritis in pregnant women.
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Breast feeding has not been recommended in azathioprine therapy because of the potential risk of immunosuppression in the infant.
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