Formulary Monographs [ACYCLOVIR, 081832]

ACYCLOVIR
NUCLEOSIDES AND NUCLEOTIDES
Effective in treating initial or recurrent herp es simplex virus, herp es
zoster and varicella zoster virus infections.
Acyclovir is generally well tolerated. GI disturbances, renal failure, local reactions at the injection site, headache and rash may occur. A finger cot or rubber glove should be utilized for ap p lication to prevent auto-innoculation of other body sites.
Adult: For the treatment of initial genital herp es: 200mg orally 5 times daily for 7-10 days. For the treatment of herpes zoster: 800mg orally 5 times daily . For chronic suppressive therapy for recurrent diseases 400mg twice daily (or 200
With systemic use:
Not known to be harmful—manufacturers advise use only when potential benefit outweighs risk.
With systemic use:
Significant amount in milk after systemic administration—not known to be harmful but manufacturer advises caution.