| Active Ingredient | GLIBENCLAMIDE |
| Therapeutic Class | SULPHONYLUREAS |
| Indications |
Diabetes Mellitus. More potent than chlorpropamide but shorter acting and not affected by renal failure. Half-life: 10 hours; Duration of Action: 24 hours. Glyburide is the micronised form More ... |
| Caution | Hypoglycemia: Occurs more commonly in elderly patients, even with low doses. It is best avoided in the elderly . c.f. prescribing in liver and renal disease p. 14; 30. |
| Dose Range |
2.5-5mg to a maximum of 20mg daily . Take with breakfast. See BDS supply protocols pg. 7. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GLICLAZIDE |
| Therapeutic Class | SULPHONYLUREAS |
| Indications | Treatment of diabetes mellitus. May be of benefit in retinopathy. |
| Caution | Gastro intestinal upset, nausea, hypoglycemia, weight gain, dizziness. c.f. prescribing in liver and renal disease p. 14; 30. |
| Dose Range |
Intial dose: 40- 80 mg daily with breakfast, gradually increasing to 320 mg daily . Doses of more than 160 mg daily are given in 2 divided doses. M odified-release: initial dose is 30 mg once daily , increasing if necessary in step s of |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GLIMEPIRIDE |
| Therapeutic Class | SULPHONYLUREAS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GLYBURIDE |
| Therapeutic Class | SULPHONYLUREAS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |