| Active Ingredient | ACETYLCYSTEINE |
| Therapeutic Class | ANTIDOTES |
| Indications |
Treatment of paracetamol overdose, if patient is seen within 20 hours after overdose of 20-30 tablets. |
| Caution | |
| Dose Range |
150mg/kg IV in 200ml of 5% dextrose over 15 minutes then 50mg/kg in 50ml 5% dextrose over 4 hours, then 100mg/kg IV in 1L 5% dextrose over 16 hours. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | CALCIUM FOLINATE |
| Therapeutic Class | ANTIDOTES |
| Indications | Antidote to folic acid antagonists, such as methotrexate. adjunct to fluorouracil in the treatment of colorectal cancer. |
| Caution | Occasional hypersensitivity, including anaphylactic reactions. |
| Dose Range |
Dosage and duration adapted according to the methotrexate regimen and the patient's ability to clear the antineoplastic. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | LEUCOVORIN |
| Therapeutic Class | ANTIDOTES |
| Indications | Antidote to folic acid antagonists, such as methotrexate. adjunct to fluorouracil in the treatment of colorectal cancer. |
| Caution | Occasional hypersensitivity, including anaphylactic reactions. |
| Dose Range | Dosage and duration adapted according to the methotrexate regimen and the patient's ability to clear the antineoplastic. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |