| Active Ingredient | AZITHROMYCIN |
| Therapeutic Class | OTHER MACROLIDES |
| Indications | Skin and soft tissue infections; respiratory tract infections, ottis media, uncomplicated genital chlamydia infections and non-gonococcal urethritis. |
| Caution | Gastrointestinal (abdominal pain, diarrhea and nausea), particularly with higher doses. Do not use with antacids. |
| Dose Range | Adult: 500mg daily for 3 day s or 500mg on first day then 250mg once daily for 4 days. Chancroid, Chlamydia: 1g stat dose. UncomplicatedGonorrhea: 2g stat dose. Pediatric: 6 months and over: 10mg/kg/day for 3 days. Tonsillitis: 2 years and over: 12mg/kg/ |
| Drug Interactions | |
| Pregnancy | Manufacturers advise use only if adequate alternatives are not available. |
| Breast Feeding | Present in milk; use only if there are no suitable alternatives. |
| Active Ingredient | CLARITHROMYCIN |
| Therapeutic Class | OTHER MACROLIDES |
| Indications |
Helicobacter pylori associated duodenal ulcers. Multiple-drug regimens have been used e.g. dual-drug (combination with omeprazole or ranitidine) ortriple-drug (combination with lansoprazole/ amoxicill More ... |
| Caution | Diarrhoea, nausea, vomiting or abdominal pain. Use with caution in patients with marked hepatic or renal impairment. May be taken with food to lessen stomach upset. Inform doctor if patient is taking More ... |
| Dose Range |
Adult: 250mg every 12 hours for 7 days, increased in severe infections to 500mg every 12 hours for up to 14 days. Pediatric: under 8kg: 7.5mg/kg twice daily ; 8-11kg (1-2 years); 62.5mg twice daily, 12-19kg (3-6 years) 125mg twice daily ; 20-29kg (7-9 |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | Clarithromycin should be used with caution in nursing women since the drug is di More ... |
| Active Ingredient | ROXITHROMYCIN |
| Therapeutic Class | OTHER MACROLIDES |
| Indications | Nongonococcal urethritis, streptococcal pharyngitis, skin and soft tissue infections, upper and lower respiratory tract infections, otitis media. |
| Caution | Nausea, diarrhea, abdominal cramps and anorexia. The serum half-life of roxithromycin may increase in the presence of severe renal or hepatic failure, and dosage modification may be required. |
| Dose Range | Adult: 150mg twice a day or 300mg once daily . Pediatric: Usual doses are 2.5 to 5mg/kg every 12 hours. See BDS supply protocols pg.3. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |